The Role Of The Histone H3 And H4 N Termini In Gene Regulation And Chromatin Structure In Saccharomyces Cerevisiae
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Chromatin Structure and Gene Expression
Author: Sarah C. R. Elgin
language: en
Publisher: Frontiers in Molecular Biology
Release Date: 2000
Since publication of the first edition in 1995, there have been significant advances and understanding of chromatin structure and its relation to gene expression. These include a high-resolution structure of the nucleosome core, discovery of the enzymes and complexes that mediate histone acetylation and deacetylation, discovery of novel ATP-dependent chromatin remodeling complexes, new insights into nuclear organization and epigenetic silencing mechanisms. In light of these advances, Chromatin Structure and Gene Expression (2ed.) includes updated chapters and additional material that introduce new concepts in the process of gene regulation in chromatin.