Practical Insights Into Atopic Dermatitis
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Practical Insights into Atopic Dermatitis
This book is a comprehensive, practical guide to the latest developments in the understanding and management of atopic dermatitis. Detailed information is provided on age-specific clinical symptoms, features, and diagnostic methods. Current theories on the pathogenesis of atopic dermatitis are closely examined, with attention to the roles played by genetic, allergic, immunologic, and skin barrier dysfunctions. In the second half of the book, the scientific background to and the practical use of the full range of treatment methods are described, covering topical agents, systemic agents, phototherapy, allergen-specific immunotherapy, and the most recently developed biologics and small molecules. This textbook will be an excellent guide to diagnosis and treatment for not only dermatologists but also practitioners in allergy and general medicine, including pediatricians, allergists, and primary care physicians. In addition, it will be of value for all scientists interested in developing new drugs for atopic dermatitis.
Exacerbating Factors in Atopic Eczema I
Author: Prof. Dr. Bilal Semih Bozdemir
language: en
Publisher: Prof. Dr. Bilal Semih Bozdemir
Release Date:
Atopic eczema, also known as atopic dermatitis, represents a chronic, inflammatory skin condition characterized by the disruption of skin integrity and function. It is one of the most prevalent dermatological disorders globally, impacting millions of people across all age groups, though it predominantly manifests in childhood. The clinical presentation of atopic eczema is marked by pruritic (itchy) and erythematous (red) lesions, which can lead to significant discomfort and adverse psychosocial effects. While the exact etiology remains multifaceted, atopic eczema is understood to arise from the interplay of genetic susceptibility, environmental factors, and immune system dysregulation. The significance of atopic eczema extends beyond its clinical manifestations. It is associated with a considerable economic burden due to healthcare costs and lost productivity, as affected individuals often seek frequent medical care and experience decreased quality of life. Furthermore, atopic eczema frequently coexists with other atopic disorders, such as asthma and allergic rhinitis, complicating the management of patients who exhibit a spectrum of allergic responses. Historically, the perception of atopic eczema as a benign condition has shifted dramatically as research has elucidated its complex pathophysiology. This chapter aims to provide a comprehensive overview of atopic eczema, emphasizing its significance on both individual and systemic levels and establishing the groundwork for further exploration into the various factors exacerbating this condition.
Pediatric Allergy: Principles and Practice
Author: Stanley J. Szefler, MD
language: en
Publisher: Elsevier Health Sciences
Release Date: 2015-08-11
The third edition of Pediatric Allergy continues this title's steadfast tradition of providing comprehensive, authoritative guidance on the day-to-day diagnosis and management of pediatric allergic and immunologic diseases. You'll have the most up-to-date research at hand thanks to an easily accessible full-color format that highlights a host of new chapters, extensive updates, and clinically focused coverage. Whether you're a student, resident, pediatrician or allergist, you'll appreciate this user-friendly and versatile source for providing optimal care! Includes diagnostic tests available for asthma, upper respiratory allergy, and more. Equips you with an understanding of the immune mechanisms underlying allergic diseases. Features coverage of drug allergies and cross-reactivity. Highlights clinical pearls discussing the best approaches to the care and treatment of pediatric patients. Appendices listing common food allergies and autoantibodies in autoimmune diseases make for quick reference to essential material. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices. Revised asthma section examines current asthma guidelines; school-centered asthma programs; exercise-induced asthma; and new directions in asthma therapy. Includes the most current knowledge relating to emerging asthma within young children, medication adherence, and the impact of infection on the natural history of asthma. New information on gene therapy, stem-cell therapy, and a host of new immunodeficiency diseases helps you obtain the best results from the therapeutics for pediatric allergic and immunologic diseases. Features brand-new chapters on immunopathology; diagnostics and management; potential immunotherapeutic strategies for treating food allergies; current status of immunotherapy for food allergy; and biologic therapies. Focused coverage of today's hot topics in pediatric allergy includes the use of targeted biologics to treat specific activation pathways leading to severe allergic diseases; defects of innate immunity; rheumatic diseases of childhood; and inflammatory disorders. Discusses new studies examining potential etiologies for the increase in food allergy and examines potential immunotherapeutic strategies for treating food allergies. New evidence-based principles of medical care help you make the best use of available medications for your patients.