Mips And Their Roles In The Exchange Of Metalloids
Download Mips And Their Roles In The Exchange Of Metalloids PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Mips And Their Roles In The Exchange Of Metalloids book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages.
MIPs and Their Roles in the Exchange of Metalloids
Author: Thomas P. Jahn
language: en
Publisher: Springer Science & Business Media
Release Date: 2011-01-11
Sixteen years have passed since human aquaporin-1 (AQP1) was discovered as the first water channel, facilitating trans-membrane water fluxes. Subsequent years of research showed that the water channel AQP1 was only the tip of an iceberg; the iceberg itself being the ubiquitous super family of membrane intrinsic proteins (MIPs) that facilitate trans-membrane transport of water and an increasing number of small, water-soluble and uncharged compounds. Here we introduce you to the superfamily of MIPs and provide a summary about our gradually refined understanding of the phylogenetic relationship of its members. This volume is dedicated to the metalloids, a recently discovered group of substrates for a number of specific MIPs in a diverse spectrum of organisms. Particular focus is given to the essential boron, the beneficial silicon and the highly toxic arsenic. The respective MIP isoforms that facilitate the transport of these metalloids include members from several clades of the phylogenetic tree, suggesting that metalloid transport is an ancient function within this family of channel proteins. Among all the various substrates that have been shown to be transported by MIPs, metalloids take an outstanding position. While water transport seems to be a common function of many MIPs, single isoforms in plants have been identified as being crucially important for the uptake of boric acid as well as silicic acid. Here, the function seems not to be redundant, as mutations in those genes render plants deficient in boron and silicon, respectively.
MIPs and Their Roles in the Exchange of Metalloids
Sixteen years have passed since human aquaporin-1 (AQP1) was discovered as the first water channel, facilitating trans-membrane water fluxes. Subsequent years of research showed that the water channel AQP1 was only the tip of an iceberg; the iceberg itself being the ubiquitous super family of membrane intrinsic proteins (MIPs) that facilitate trans-membrane transport of water and an increasing number of small, water-soluble and uncharged compounds. Here we introduce you to the superfamily of MIPs and provide a summary about our gradually refined understanding of the phylogenetic relationship of its members. This volume is dedicated to the metalloids, a recently discovered group of substrates for a number of specific MIPs in a diverse spectrum of organisms. Particular focus is given to the essential boron, the beneficial silicon and the highly toxic arsenic. The respective MIP isoforms that facilitate the transport of these metalloids include members from several clades of the phylogenetic tree, suggesting that metalloid transport is an ancient function within this family of channel proteins. Among all the various substrates that have been shown to be transported by MIPs, metalloids take an outstanding position. While water transport seems to be a common function of many MIPs, single isoforms in plants have been identified as being crucially important for the uptake of boric acid as well as silicic acid. Here, the function seems not to be redundant, as mutations in those genes render plants deficient in boron and silicon, respectively.
Metalloids in Biology
Metalloids belong to class of elements that exhibit physiochemical characteristics intermediating between those of metals and non-metals. Some are quasi-essential for the overall growth and development of plants. Silicon, for instance, enhances plant structural integrity, while boron is crucial for cell wall formation, and selenium acts as an antioxidant but some are toxic, like germanium (Ge) and arsenic (As), as they threaten the soil ecosystem and human health. Metalloid toxicity hinges on their cellular concentrations ,where low levels aid plant development ,whereas high levels cause harmful effects. Thus, it is crucial to encompass the underlying detoxification mechanisms behind metalloid uptake by root system, their transport to other tissues, and their redistribution within and between cells. This book provides a comprehensive elucidation of the valuable insights of metalloids in green agriculture emphasizing management strategies to mitigate their adverse effects through various detoxification pathways, including cell complexation, cell wall binding, efflux, vacuolar sequestration and ultimately redistribution. Key features:1.Explores databases of metalloid distribution in plants and other habitats. 2.Deliberates about metalloid transporters and detoxification strategies in plants. 3. Describes interaction of metalloids with microbes and their impact on ecophysiology. 4. Unravels the mysteries of metalloid stress in plants by using multi-omics approaches. 5. Covers biological applications of metalloids in sustainable agricultural practices and in human health.This book is aimed to give updated and scientific insights to readers and researchers associated with plant stress physiology, agricultural sciences and environmentalists working for the well-being of the environment. Apart from these, the present book will also be boon for scientists, farmers, teachers and undergraduate and post graduate students as it provides a detailed account of distribution, biochemistry, detoxification mechanisms, and biological applications of metalloids.