Measurements Modelling And Simulation Of Dynamic Systems

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Measurements, Modelling and Simulation of Dynamic Systems

Author: Edward Layer
language: en
Publisher: Springer Science & Business Media
Release Date: 2009-12-30
The development and use of models of various objects is becoming a more common practice in recent days. This is due to the ease with which models can be developed and examined through the use of computers and appropriate software. Of those two, the former - high-speed computers - are easily accessible nowadays, and the latter - existing programs - are being updated almost continuously, and at the same time new powerful software is being developed. Usually a model represents correlations between some processes and their interactions, with better or worse quality of representation. It details and characterizes a part of the real world taking into account a structure of phenomena, as well as quantitative and qualitative relations. There are a great variety of models. Modelling is carried out in many diverse fields. All types of natural phenomena in the area of biology, ecology and medicine are possible subjects for modelling. Models stand for and represent technical objects in physics, chemistry, engineering, social events and behaviours in sociology, financial matters, investments and stock markets in economy, strategy and tactics, defence, security and safety in military fields. There is one common point for all models. We expect them to fulfil the validity of prediction. It means that through the analysis of models it is possible to predict phenomena, which may occur in a fragment of the real world represented by a given model. We also expect to be able to predict future reactions to signals from the outside world.
Measurements, Modelling and Simulation of Dynamic Systems

This book discusses an analog-to-digital system intended to dynamic measurement, particularly for non-electrical quantities. The construction and properties of measurement sensors are analyzed in detail, as these represent the primary components for all measurement systems. Procedures for signal noise reduction are presented based on the time window function and a digital Kalman filter. Also covered in this book are the methods of modeling, model development and identification procedures on the basis of measurement data. The theory of maximum errors is applied in order to determine mapping errors of models in case of non-standard input signals. This is based on signals maximizing the chosen error functional. The existence and attainability of such signals is proved and the algorithms for their determination are presented. Detailed calculation methods, based on dedicated numerical procedures are demonstrated, which allow the integral-square error as well as the absolute error to be determined. The problems presented in the book are relevant to a wide range of applications where there is a requirement to determine the accuracy of indeterminate dynamic signals such as occurs in the fields of engineering, medicine, biology, physics etc. This book will interest researchers, scientists, engineers and graduate students in many disciplines, who make use of measurements, modelling and computer simulation. .
Dynamic Systems Biology Modeling and Simulation

Author: Joseph DiStefano III
language: en
Publisher: Academic Press
Release Date: 2015-01-10
Dynamic Systems Biology Modeling and Simuation consolidates and unifies classical and contemporary multiscale methodologies for mathematical modeling and computer simulation of dynamic biological systems – from molecular/cellular, organ-system, on up to population levels. The book pedagogy is developed as a well-annotated, systematic tutorial – with clearly spelled-out and unified nomenclature – derived from the author's own modeling efforts, publications and teaching over half a century. Ambiguities in some concepts and tools are clarified and others are rendered more accessible and practical. The latter include novel qualitative theory and methodologies for recognizing dynamical signatures in data using structural (multicompartmental and network) models and graph theory; and analyzing structural and measurement (data) models for quantification feasibility. The level is basic-to-intermediate, with much emphasis on biomodeling from real biodata, for use in real applications. - Introductory coverage of core mathematical concepts such as linear and nonlinear differential and difference equations, Laplace transforms, linear algebra, probability, statistics and stochastics topics - The pertinent biology, biochemistry, biophysics or pharmacology for modeling are provided, to support understanding the amalgam of "math modeling with life sciences - Strong emphasis on quantifying as well as building and analyzing biomodels: includes methodology and computational tools for parameter identifiability and sensitivity analysis; parameter estimation from real data; model distinguishability and simplification; and practical bioexperiment design and optimization - Companion website provides solutions and program code for examples and exercises using Matlab, Simulink, VisSim, SimBiology, SAAMII, AMIGO, Copasi and SBML-coded models - A full set of PowerPoint slides are available from the author for teaching from his textbook. He uses them to teach a 10 week quarter upper division course at UCLA, which meets twice a week, so there are 20 lectures. They can easily be augmented or stretched for a 15 week semester course - Importantly, the slides are editable, so they can be readily adapted to a lecturer's personal style and course content needs. The lectures are based on excerpts from 12 of the first 13 chapters of DSBMS. They are designed to highlight the key course material, as a study guide and structure for students following the full text content - The complete PowerPoint slide package (~25 MB) can be obtained by instructors (or prospective instructors) by emailing the author directly, at: [email protected]