Decoding Multiple Sclerosis
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Precision Medicine in Neurodegenerative Disorders
Precision Medicine in Neurodegenerative Disorders, Part Two, Volume 193 in the Handbook of Clinical Neurology deals with the "How" in the reconfiguration of our approach to slow accelerated brain aging. The book rethinks animal models on which therapies are tested, outlines the progress and expected changes in biological subtyping efforts using lysosomal, endosomal, mitochondrial, immune dysregulation, and inflammatory mechanisms of disease pathophysiology, and the growing role of microbiome in shaping disease. The volume separates the potentially disease-modifying neurorescue and neurorestoration, (e.g., gene therapy and cell replacement therapy) from true precision "medicine"–matching biology with the mechanism of intervention of interest. Specific chapters are dedicated to the promise and challenges of extracellular vesicles for both diagnosis and treatment, the growing application of digital measures and other evaluations of clinical response, the nuts and bolts of novel adaptive clinical trial designs, and the regulatory changes needed to facilitate drug development for disease-modification purposes. - Summarizes theory and research on precision medicine in neurodegenerative disorders - Covers basic biology, clinical trials and therapeutics - Includes disease mechanisms, genetic subtypes, and more
Decoding Multiple Sclerosis
Author: Nilesh Panchal
language: en
Publisher: Independently Published
Release Date: 2024-11-15
Decoding Multiple Sclerosis: A Complete Guide to Understanding and Managing MS offers a comprehensive and accessible exploration of one of the most complex neurological conditions. This book delves into every aspect of Multiple Sclerosis, from its mysterious causes and diverse symptoms to the latest diagnostic tools and cutting-edge treatment options. With a focus on empowering readers, it provides practical strategies for managing daily life, maintaining mental and physical well-being, and navigating the emotional and social challenges of living with MS. Packed with insights from medical experts, patient stories, and the latest research, this guide serves as a vital resource for anyone affected by MS-patients, caregivers, and medical professionals alike-helping them decode the complexities of this condition and find pathways to hope, resilience, and a better quality of life.
Nanomedicine for Inflammatory Diseases
Author: Lara Scheherazade Milane
language: en
Publisher: CRC Press
Release Date: 2017-09-19
Nanomedicine for Inflammatory Diseases is a cutting-edge resource for clinicians and scientists alike, working at the intersection of development and clinical therapeutics. This text is ideal for graduate level courses in nanomedicine, translational medicine, or inflammatory disease. This book is a progressive hallmark in translational medicine as it unites clinicians treating inflammatory disease with scientists developing experimental nanomedicine therapeutics. The commonality is made through a translational nanomedicine expert – bridging the gap between the laboratory benchtop and the clinical bedside.