Computational And Experimental Approaches On Soft Tissues Biomechanics And Mechanobiology
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Computational and Experimental Approaches on Soft Tissues Biomechanics and Mechanobiology
Soft tissues, which encompass all organs of the body, such as the brain, muscles, and tendons, play a crucial role in maintaining the normal function in the human body. Understanding the biomechanics and mechanobiology of these tissues by integrating computational and experimental approaches is essential for advancing the clinical treatments, medical device development and overall healthcare. This topic outlines multidisciplinary research on understanding soft tissues’ biomechanics and mechanobiology under various physiological and pathological conditions. The proposed topic aims to combine experimental and computational methods to gain insights into the complex mechanical behaviors of soft tissues. To achieve this goal, this Research Topic will focus on some specific objectives like developing novel computational models to elucidate soft tissue behavior and quantifying the effects of diseases, characterizing soft tissue properties by advancing experimental techniques, such as tissue testing, imaging and microscale analysis. This will help in characterizing the mechanical properties and structural behavior of various soft tissues under both physiological and pathological conditions. We welcome the studies that investigates mechanobiological processes such as tissue remodeling, adaption, and injury, by integrating computational models with experimental data to gain insights into mechanical behavior. The studies that apply the findings from this research to improve clinical applications, such as subject-specific treatment, development of medical devices and regenerative medicine. This topic will also cover the interdisciplinary research by integrating biomechanics, biology, engineering, clinical studies, and imaging techniques. • Computational modeling development • Machine learning applications • Experimental characterization • Imaging processing techniques • Mechanobiological processes • Disease mechanisms • Application in clinical treatments and medical devices
Biomechanics
Biomechanics is a component of Encyclopedia of Physical Sciences, Engineering and Technology Resources in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. The enormous progress in the field of health sciences that has been achieved in the 19th and 20th centuries would have not been possible without the enabling interaction and support of sophisticated technologies that progressively gave rise to a new interdisciplinary field named alternatively as bioengineering or biomedical engineering. Although both terms are synonymous, the latter is less general since it limits the field of application to medicine and clinical practice, while the former covers semantically the whole field of interaction between life sciences and engineering, thus including also applications in biology, biochemistry or the many '-omics'. We use in this book the second, with more general meaning, recalling the very important relation between fundamental science and engineering. And this also recognizes the tremendous economic and social impacts of direct application of engineering in medicine that maintains the health industry as one with the fastest growth in the world economy. Biomechanics, in particular, aims to explain and predict the mechanics of the different components of living beings, from molecules to organisms as well as to design, manufacture and use of any artificial device that interacts with the mechanics of living beings. It helps, therefore, to understand how living systems move, to characterize the interaction between forces and deformation along all spatial scales, to analyze the interaction between structural behavior and microstructure, with the very important particularity of dealing with adaptive systems, able to adapt their internal structure, size and geometry to the particular mechanical environment in which they develop their activity, to understand and predict alterations in the mechanical function due to injuries, diseases or pathologies and, finally, to propose methods of artificial intervention for functional diagnosis or recovery. Biomechanics is today a very highly interdisciplinary subject that attracts the attention of engineers, mathematicians, physicists, chemists, material specialists, biologists, medical doctors, etc. They work in many different topics from a purely scientific objective to industrial applications and with an increasing arsenal of sophisticated modeling and experimental tools but always with the final objectives of better understanding the fundamentals of life and improve the quality of life of human beings. One purpose in this volume has been to present an overview of some of these many possible subjects in a self-contained way for a general audience. This volume is aimed at the following major target audiences: University and College Students, Educators, Professional Practitioners, and Research Personnel.
Advances in Biomechanics and Tissue Regeneration
Author: Mohamed H. Doweidar
language: en
Publisher: Academic Press
Release Date: 2019-08-13
Advances in Biomechanics and Tissue Regeneration covers a wide range of recent development and advances in the fields of biomechanics and tissue regeneration. It includes computational simulation, soft tissues, microfluidics, the cardiovascular system, experimental methods in biomechanics, mechanobiology and tissue regeneration. The state-of-the-art, theories and application are presented, making this book ideal for anyone who is deciding which direction to take their future research in this field. In addition, it is ideal for everyone who is exploring new fields or currently working on an interdisciplinary project in tissue biomechanics. - Combines new trends in biomechanical modelling and tissue regeneration - Offers a broad scope, covering the entire field of tissue biomechanics - Contains perspectives from engineering, medicine and biology, thus giving a holistic view of the field