Beyond Imaging
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Beyond Imaging
When most of us hear the word ultrasound, we typically think of diagnostic imaging; especially in regard to its use in obstetrics. Ultrasound, however, can also be used for a wide variety of therapeutic applications, which the author has chosen as the theme of this book. The book begins with a primer on sound waves, which are followed with some basics on imaging. Next are descriptions of the evolving technology, with a specific emphasis on medical applications. Examples are given of the different procedures that are carried out using sophisticated, non-invasive, image-guided devices. Each procedure is carefully explained with the help of many detailed illustrations. Examples of these include the destruction of tumors deep within the body using highly focused ultrasound beams. Especially impressive are the treatments that are guided with realtime MRI. One in particular is employed for opening barriers in the brain to facilitate the delivery of a range of agents for treating conditions such as Alzheimer’s disease. For almost thirty years, Victor Frenkel has worked as a teacher, mentor, and research scientist at medical schools, engineering departments, and government institutions. Along the way he made his own contributions in the field of therapeutic ultrasound. These include the development of novel treatment protocols, and also designing and building the devices used to carry them out. Told with easy-to-follow language, including key historical and cultural perspectives, this book is meant for anyone who loves cutting edge technology, especially pertaining to medical treatments.
Scanning Probe Microscopies Beyond Imaging
This first book to focus on the use of SPMs to actively manipulate molecules and nanostructures on surfaces goes way beyond conventional treatments of scanning microscopy merely for imaging purposes. It reviews recent progress in the use of SPMs on such soft materials as polymers, with a particular emphasis on chemical discrimination, mechanical properties, tip-induced reactions and manipulations, as well as their nanoscale electrical properties. Detailing the practical application potential of this hot topic, this book is of great interest to specialists of wide-ranging disciplines, including physicists, chemists, materials scientists, spectroscopy experts, surface scientists, and engineers.
Cellular Imaging Techniques for Neuroscience and Beyond
Author: Floris G. Wouterlood
language: en
Publisher: Academic Press
Release Date: 2012-12-06
The imaging of small cellular components requires powerful instruments, and an entire family of equipment and techniques based on the confocal principle has been developed over the past 30 years. Such methods are commonly used by neuroscience researchers, but the majority of these users do not have a microscopy or a cell biology backgrounds and do can encounter difficulties in obtaining and interpreting results. This volume brings experts in high-resolution optical microscopy applications in neuroscience and cell biology together to document the state of the art. Outlining what is currently possible, the volume also discusses promising developments for the future and aids readers in selecting the most scientifically meaningful approach to solve their questions. Each chapter discusses instrumentation and technology in relationship to application in research. All of the common and cutting edge trends are covered - fluorescence / laser electron / nonlinear microscopy, infrared fluorescence, multiphoton imaging, tomography, FRAP, live imaging, STED, PALM/STORM, etc. - Single and multiphoton confocal microscopy, and 4-pi confocal microscopy - Obtaining nanoresolution via photoactivation localization microscopy (PALM) - Several procedures that correlate observations in optical fluorescence microscopy and electron microscopy - Study of morphology and function via high-resolution fluorescence procedures - Additional high-resolution microscopic techniques