What Is A Good Colonoscopy Results
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Advances in Colonoscopy, An Issue of Gastrointestinal Endoscopy Clinics
Author: Douglas K. Rex
language: en
Publisher: Elsevier Health Sciences
Release Date: 2015-06-03
Colonoscopy is the bread and butter for endoscopists and advances in the procedure to reduce time, improve efficiency, and prevent errors are very important for this group. The newest advances look at colonoscopy efficiency and a better way to target tissue sampling, which avoids random biopsies and instead looks at ways to predict areas for sampling. The Guest Editors have selected top experts to provide these important updates and they also address current thinking that questions the continued value of colonoscopies as predictors of colon cancer. The issue will be a very popular one, and it needs to be heavily promoted.
Identifying Clinically Relevant Transcriptional Signatures and Methylation Profiles in the Course, Treatment and Outcome of Colorectal Cancer
Despite major efforts to stratify colorectal cancer patients, only a few prognostic and predictive biomarkers are still used in clinical practice. Inter- and intratumoral heterogeneity is one of the factors influencing strategies for biomarker identification and their implementation in clinical decisions. Recent characterization of consensus molecular subtypes has demonstrated the importance of transcriptome analysis, but the need for in-depth analysis considering other parameters has become apparent. Strategies to study and understand inter- and intratumoral heterogeneity at the tumor tissue level, focusing on gene expression, transcriptomics, and epigenetics, may improve colorectal cancer classification and lead to the identification of biomarkers of prognostic and predictive importance to complement genetics. They could lead to a better understanding of the causes of treatment failure and disease recurrence and thus to new possibilities for patient stratification. Liquid biopsy is currently an effective strategy to capture tumor heterogeneity in non-invasive monitoring of disease progression and recurrence.
Timely Diagnosis of Colorectal Cancer
This book summarizes current knowledge and outlines directions for the future on how to improve the art of diagnosing colorectal cancer with emphasis on timeliness, one of the most vital issues in cancer management. Using a comprehensive, multi-discliplinary approach, it provides an overview of decisive factors in timely diagnosis of colorectal cancer from symptom scores and symptom awareness to technical aspects. The book starts by discussing early diagnosis from the perspective of patients, including the importance of awareness in the general population as well as psychological aspects. It then goes on to discuss issues of importance to clinicians, such as fast tracking, laboratory testing, improving technical skills and optimizing endoscopy services. In addition, more practical issues such as cost-effectiveness and auditing are also extensively discussed. By focusing on one specific but common form of cancer the content translates well across the scope of other cancer types and can be used by professionals working on different cancer types. This book provides clinicians, clinical researchers and policymakers with a comprehensive overview of the field of timeliness in diagnosing colorectal cancer. By addressing the challenges posed in the management of symptomatic patients it informs and educates the experts and could help improve diagnosis.