What Are The Functions Of Epidermal Cells
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The Immune Functions of Epidermal Langerhans Cells
Author: Heidrun Moll
language: en
Publisher: Springer Science & Business Media
Release Date: 2013-11-21
This book is about the phenotypic and functional features of epidermal Langerhans cells in experimental models and in clinical medicine. Langerhans cells, members of the dendritic cell system in the skin, are critically involved in the regulation of cell-mediated immune responses and gain increasing attention in a wide spectrum of clinical areas such as allergy, autoimmunity, transplantation and resistance to tumors and infections. The book covers the latest, most timely developments in this rapidly advancing field. Leading researchers describe functional analyses at the cell and molecular level, elucidating processes related to antigen presentation and the role of cytokines, and discuss perspectives for a future use of Langerhans cells and other dendritic cells in the immunotherapy of various diseases.
Epidermal Langerhans Cells
Epidermal Langerhans Cells focuses on epidermal Langerhans cells (LCs) and the important role they play in the induction of contact hypersensitivity and graft rejection. This in-depth work discusses how these antigen-presenting cells are modulated by various physicochemical agents (such as UV light) and how they can be infected by the AIDS virus. It also reveals that cytokines mediate their development into potent T cell-stimulatory dendritic cells. This comprehensive review covers important experimental details and methods, and fascinating information on LCs. It also provides an overview of the immune system as it relates to the skin in health and disease. This up-to-date publication is an indispensable resource for all investigative and clinical dermatologists, as well as immunologists interested in antigen-presenting cells.
Dendritic Epidermal T Cells in Wound Healing and Cancer
Topic Editor Prof. Zhinan Yin is the co-founder of JIDEI Kongming Biotech. All other Topic Editors declare no competing interests with regards to the Research Topic subject