Understanding Human Dna
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Mapping and Sequencing the Human Genome
Author: National Research Council
language: en
Publisher: National Academies Press
Release Date: 1988-01-01
There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
The Human DNA Manual
Author: Dr. Melita Irving
language: en
Publisher: Haynes Publishing UK
Release Date: 2019-11-19
The Human DNA Manual aims to enlighten and entertain the genetically curious layperson on all aspects of our DNA and genetic code. An introductory section covers the basic concepts of genetics and debunks some of the confusion that stems from associated jargon. A history of DNA discovery explains the role of this molecule-of-inheritance and how it conveys the recipe for life, including how to extract your own DNA at home using every day household items. Discussing the relevance of DNA in the past, present and the future, author Melita Irving also covers the potential influence genes have in driving evolution; the concept of bringing back notable historical species from extinction, and the widespread role of DNA in everyday practices. Current issues, such as genetic conditions and the latest medical breakthroughs in detecting them, forensic science, gene therapy and sequencing are all clearly explained. Finally, the book looks at the future of genes and examine the impact DNA will have on the lives of the next generation — the epigenetics era and potentially heritable consequences of environmental exposures, the contribution of genetic engineering to a functioning society, the concept of gene editing in reproductive medicine, the slippery slope to a 'superhuman' race, and human cloning, as well as the potential for the development of new therapies using gene technology.
Who We Are and How We Got Here
Author: David Reich
language: en
Publisher: Oxford University Press
Release Date: 2018-03-29
The past few years have seen a revolution in our ability to map whole genome DNA from ancient humans. With the ancient DNA revolution, combined with rapid genome mapping of present human populations, has come remarkable insights into our past. This important new data has clarified and added to our knowledge from archaeology and anthropology, helped resolve long-existing controversies, challenged long-held views, and thrown up some remarkable surprises. The emerging picture is one of many waves of ancient human migrations, so that all populations existing today are mixes of ancient ones, as well as in many cases carrying a genetic component from Neanderthals, and, in some populations, Denisovans. David Reich, whose team has been at the forefront of these discoveries, explains what the genetics is telling us about ourselves and our complex and often surprising ancestry. Gone are old ideas of any kind of racial 'purity', or even deep and ancient divides between peoples. Instead, we are finding a rich variety of mixtures. Reich describes the cutting-edge findings from the past few years, and also considers the sensitivities involved in tracing ancestry, with science sometimes jostling with politics and tradition. He brings an important wider message: that we should celebrate our rich diversity, and recognize that every one of us is the result of a long history of migration and intermixing of ancient peoples, which we carry as ghosts in our DNA. What will we discover next?