The Uncoupling Principle
Download The Uncoupling Principle PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get The Uncoupling Principle book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages.
Principles of Bioenergetics
Author: Vladimir P. Skulachev
language: en
Publisher: Springer Science & Business Media
Release Date: 2012-12-15
Principles of Bioenergetics summarizes one of the quickly growing branches of modern biochemistry. Bioenergetics concerns energy transductions occurring in living systems and this book pays special attention to molecular mechanisms of these processes. The main subject of the book is the "energy coupling membrane" which refers to inner membranes of intracellular organelles, for example, mitochondria and chloroplasts. Cellular cytoplasmic membranes where respiratory and photosynthetic energy transducers, as well as ion-transporting ATP-synthases (ATPases) are also part of this membrane. Significant attention is paid to the alternative function of mitochondria as generators of reactive oxygen species (ROS) that mediate programmed death of cells (apoptosis and necrosis) and organisms (phenoptosis). The latter process is considered as a key mechanism of aging which may be suppressed by mitochondria-targeted antioxidants.
Principles of Perinatal-Neonatal Metabolism
Author: Richard M. Cowett
language: en
Publisher: Springer Science & Business Media
Release Date: 2012-12-06
PRINCIPLES OF PERINATAL-NEONATAL METABOLISM, SECOND EDITION assembles a stellar international group of contributors to examine the various aspects of metabolism in the human adult during pregnancy, in the fetus, and in the newborn. Completely updated and revised with more than 17 new chapters, the book is divided into five sections: 1) Methodology and General Principles; 2) Maternal Metabolism During Pregnancy; 3) Fetal-Placental Metabolism; 4) Organ Specific Metabolism During the Perinatal Period; 5) Neonatal Metabolism. New to the second edition are discussions of methodologies using molecular biology technqiues, expanded coverage of central nervous system metabolism, and an entirely new section on organ-specific metabolism that is organized by organ-system. A must for every physician who cares for the pregnant patient and her child. From reviews of the critically acclaimed first edition: "an incredible amount of information...of utmost value not only to the basic investigator but also to the clinician." - JAMA "a first-rate reference textbook that should be on the shelves of every institution that provides care for the pregnant women or her children" - NEJM "I know of no other volume in which these important topics are integrated into a single text...I enthusiastically recommend it as a valuable reference to researchers, clinicians, fellows, and students." - TEM
Principles of Molecular Medicine
Author: Marschall S. Runge
language: en
Publisher: Springer Science & Business Media
Release Date: 2007-11-18
The concept of molecular medicine dates back to Linus means that there are many new opportunities and challenges Pauling, who in the late 1940s and early 1950s generalized for clinical medicine. One of the effects of the completion of from the ideas that came from the study of the sickle cell the Human Genome Project is the increasing application of hemoglobin molecule. With the first cloning of human genes the fields of molecular biology and genetics to the und- about 1976, molecular genetics took the molecular perspec- standing and management of common diseases. Assimi- tive on disease to the level of DNA. The term molecular tion of the new developments since the first edition has been medicine achieved wide currency in the 1980s with the ably accomplished by Drs. Runge and Patterson with the assignment of this designation to journals, at least one soci- help of their many knowledgeable authors. ety, institutes, and academic divisions of departments of in- As was evident in the first edition, molecular genetics is ternal medicine. Undoubtedly, molecular medicine has been involved in every specialty of medicine. A recurrent theme abetted by the Human Genome Project, which has aided in that edition, perhaps even more striking in the present one, greatly in the molecular characterization of disease.