The Integrative Functions Of The Basal Ganglia
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The Integrative Functions of The Basal Ganglia
This volume is the first comprehensive and single-authored book on the functions of the basal ganglia. The goal is to provide a new synthesis of diverse areas of research on the basal ganglia, from cellular mechanisms of synaptic transmission and plasticity to neural circuit mechanisms underlying behavior. A global theory of basal ganglia function incorporating research from the last 40 years is presented. I hope to explain for the first time how the basal ganglia generate behavior, how they contribute to learning and memory, and how impairments in basal ganglia function can lead to neurological and psychiatric disorders. Features The only single-authored book on the basal ganglia with coverage of the latest literature Spans multiple levels of analysis, from cellular physiology to behavior Includes coverage of clinical symptoms, encompassing neuropsychology, movement disorders, and psychiatric disorders Discusses the role of the basal ganglia in learning and memory
The Basal Ganglia
This groundbreaking text takes current knowledge of the basal ganglia far from well-known motor-based models to a more inclusive understanding of deep-brain structure and function. Synthesizing diverse perspectives from across the brain-behavioral sciences, it tours the neuroanatomy and circuitry of the basal ganglia, linking their organization to their controlling functions in core cognitive, behavioral, and motor areas, both normative and disordered. Interactions between the basal ganglia and major structures of the brain are identified in their contributions to a diverse range of processes, from language processing to decision-making, emotion to visual perception, motivation to intent. And the basal ganglia are intimately involved in the mechanisms of dysfunction, as evinced by chapters on dyskinesia, Parkinson’s disease, neuropsychiatric conditions, and addictions. Included in the coverage: Limbic-basal ganglia circuits: parallel and integrative aspects. Dopamine and its actions in the basal ganglia system. Cerebellar-basal ganglia interactions. The basal ganglia contribution to controlled and automatic processing. The basal ganglia and decision making in neuropsychiatric disorders. The circuitry underlying the reinstatement of cocaine seeking: modulation by deep brain stimulation. The basal ganglia and hierarchical control in voluntary behavior. Its breadth and depth of scholarship and data should make The Basal Ganglia a work of great interest to cognitive psychologists and neuroscientists, neuropsychologists, neurologists, neuropsychiatrists, and speech-language pathologists.
Models of Information Processing in the Basal Ganglia
This book brings together the biology and computational features of the basal ganglia and their related cortical areas along with select examples of how this knowledge can be integrated into neural network models. Recent years have seen a remarkable expansion of knowledge about the anatomical organization of the part of the brain known as the basal ganglia, the signal processing that occurs in these structures, and the many relations both to molecular mechanisms and to cognitive functions. This book brings together the biology and computational features of the basal ganglia and their related cortical areas along with select examples of how this knowledge can be integrated into neural network models. Organized in four parts - fundamentals, motor functions and working memories, reward mechanisms, and cognitive and memory operations - the chapters present a unique admixture of theory, cognitive psychology, anatomy, and both cellular- and systems- level physiology written by experts in each of these areas. The editors have provided commentaries as a helpful guide to each part. Many new discoveries about the biology of the basal ganglia are summarized, and their impact on the computational role of the forebrain in the planning and control of complex motor behaviors discussed. The various findings point toward an unexpected role for the basal ganglia in the contextual analysis of the environment and in the adaptive use of this information for the planning and execution of intelligent behaviors. Parallels are explored between these findings and new connectionist approaches to difficult control problems in robotics and engineering. Contributors James L. Adams, P. Apicella, Michael Arbib, Dana H. Ballard, Andrew G. Barto, J. Brian Burns, Christopher I. Connolly, Peter F. Dominey, Richard P. Dum, John Gabrieli, M. Garcia-Munoz, Patricia S. Goldman-Rakic, Ann M. Graybiel, P. M. Groves, Mary M. Hayhoe, J. R. Hollerman, George Houghton, James C. Houk, Stephen Jackson, Minoru Kimura, A. B. Kirillov, Rolf Kotter, J. C. Linder, T. Ljungberg, M. S. Manley, M. E. Martone, J. Mirenowicz, C. D. Myre, Jeff Pelz, Nathalie Picard, R. Romo, S. F. Sawyer, E Scarnat, Wolfram Schultz, Peter L. Strick, Charles J. Wilson, Jeff Wickens, Donald J. Woodward, S. J. Young