The Hidden World Of Protein Aggregation


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The Hidden World of Protein Aggregation


The Hidden World of Protein Aggregation

Author:

language: en

Publisher: Elsevier

Release Date: 2024-05-30


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The Hidden World of Protein Aggregation, Volume 206 provides a comprehensive exploration of protein aggregation, uncovering the factors behind the formation of amorphous aggregates and ordered structures called amyloid fibrils. It delves into the advantages and disadvantages of protein aggregates, addressing topics such as cytotoxicity and disorders linked to misfolding. Specific chapters in this release include Protein Aggregation: An Overview, Pathways of Amyloid Fibril Formation and Aggregation, Factors Influencing Amyloid Fibril Formation, Morphological Features and Types of Aggregated Structures, Each big journey starts with a first step: Importance of Oligomerization, Liquid-Liquid Phase Separation as Triggering Factor of Fibril Formation, and more.Additional sections cover Experimental Techniques for Detecting and Evaluating the Amyloid Fibrils, Prediction of Protein Aggregation, Amyloid Fibril Cytotoxicity and Associated Disorders, Inhibitors of Amyloid Fibril Formation, Therapeutic Approaches in Proteinopathies, Functional Amyloids, Biotechnological Applications of Amyloid Fibrils, and The Hidden World of Protein Aggregation. - Provides an introduction to the folding of protein and associated conditions leading to aggregation and linked pathology - Discusses structural biology and computational methodologies for analysis of protein (mis)folding and aggregation - Describes functional amyloids and their biotechnological applications

The Hidden World Beneath


The Hidden World Beneath

Author: Dr. Ravindra Goswami, Dr. Vishwajeet Singh, Dr. Anita Chauhan, Dr. Rashmi Vamil, Prof. Seema Bhadauria

language: en

Publisher: Notion Press

Release Date: 2025-02-13


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The world beneath our feet is often overlooked, hidden from sight and, for many, from thought. Yet, the soil is teeming with life—a vibrant ecosystem that plays a crucial role in the health of our planet. This book, The Hidden World Beneath: An Exploration of Soil Fungi, seeks to illuminate the fascinating world of fungi that live below ground and their profound impact on our ecosystems. Throughout this book, I and my coauthors aim to present a balanced view of soil fungi by covering various aspects of their biology, ecology, and applications. Whether you're a student of biology, a farmer interested in sustainable practices, or a curious reader fascinated by the natural world, my goal is to provide insights that deepen your understanding of fungi and their place in the web of life. One of the unique aspects of this book is its emphasis on both the scientific and practical implications of soil fungi. While we cover the latest research and findings, realworld examples, and potential applications of fungal knowledge in agriculture and conservation. This combination is intended to make the book accessible to both academic readers and those seeking practical insights.

Protein Misfolding, Aggregation and Conformational Diseases


Protein Misfolding, Aggregation and Conformational Diseases

Author: Vladimir N. Uversky

language: en

Publisher: Springer Science & Business Media

Release Date: 2007-11-24


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Research indicates that most neurodegenerative diseases, systemic amyloidoses and many others, arise from the misfolding and aggregation of an underlying protein. This is the first book to discuss significant achievements in protein structure-function relationships in biochemistry, molecular biology and molecular medicine. The authors summarize recent progress in the understanding of the relationships between protein misfolding, aggregation and development of protein deposition disorders.