The Foundations Of Population Genetics

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The Foundations of Population Genetics

An accessible but rigorous treatment of the theoretical foundations of population genetics. Population genetics—the branch of evolutionary biology concerned with understanding how and why populations’ genetic compositions change over time—rests on a well-developed theoretical foundation that draws on genetics, mathematics, and computer science. This textbook provides an approachable but rigorous treatment for advanced undergraduate and graduate students interested in building a quantitative understanding of the genetics of evolution. Existing texts either assume very mathematically advanced readers, or avoid much of the underlying theory, instead focusing on current methods of data analysis. In contrast, The Foundations of Population Genetics develops the theory from first principles. Requiring only confidence in algebra, this self-contained, student-friendly book illustrates the conceptual framework, terminology, and methods of mathematical modeling. It progressively introduces concepts from genetics as needed, while emphasizing biological implications throughout. As a result, readers come away with a deep understanding of the structure of population genetics without needing to master its mathematics. Connects theory with the most recent genetic data better than existing texts Features engaging real-world examples and extensive original figures Provides dozens of carefully scaffolded questions that deepen the reader's understanding of key concepts Ideal as a succinct reference for established scientists in biology, medicine, and computer science Instructor resources available
Population Genetics

This book aims to make population genetics approachable, logical and easily understood. To achieve these goals, the book’s design emphasizes well explained introductions to key principles and predictions. These are augmented with case studies as well as illustrations along with introductions to classical hypotheses and debates. Pedagogical features in the text include: Interact boxes that guide readers step-by-step through computer simulations using public domain software. Math boxes that fully explain mathematical derivations. Methods boxes that give insight into the use of actual genetic data. Numerous Problem boxes are integrated into the text to reinforce concepts as they are encountered. Dedicated website at www.wiley.com/go/hamiltongenetics This text also offers a highly accessible introduction to coalescent theory, the major conceptual advance in population genetics of the last two decades.
Foundations of Mathematical Genetics

Author: Anthony William Fairbank Edwards
language: en
Publisher: Cambridge University Press
Release Date: 2000-01-13
In this 2000 second edition of the classic work Foundations of Mathematical Genetics a definitive account is given of the basic models of population genetics, together with the historical origins of developments since 1908. Existing texts in mathematical population genetics have revealed the need for a careful study of the foundations of the field which have tended to be neglected in the past. This book satisfies that need, treating the simple deterministic models for random-mating diploid populations in depth, though without sacrificing clarity of expression. In the new edition, coverage has been extended with the provision of an extra chapter on the Fundamental Theorem of Natural Selection. This book is written for those interested in the mathematical aspects of genetics, ecology and biology. Both students of mathematical genetics and historians of the subject will find it a definitive statement of the origins of modern mathematical population genetics.