Targeting Signalling Pathways In Inflammatory Diseases

Targeting signalling pathways in inflammatory diseases

Targeting Cellular Signalling Pathways in Lung Diseases

The book comprehensively reviews and provides detailed insight into the cellular and molecular signalling mechanisms involved in pathophysiology of various respiratory diseases, towards developing effective therapeutic strategies in the management and treatment of lung disease. It also covers promising advances in the field of therapeutics that could lead to novel clinical therapies capable of preventing or reversing the disease features including novel strategies for targeting chronic lung diseases using advanced drug delivery systems. Importantly, the book examines the significance and relevance of the plant extracts and their constituents with therapeutic efficiencies against lung diseases. As such, the book offers a blend of translational, biological, chemical, and drug delivery aspects relevant to respiratory diseases, thus, offering a valuable resource for pulmonologists and translational researchers working in the field of pulmonary biology and respiratory medicine.

Novel Targets for Chronic Inflammatory Diseases: Focus On Therapeutic Drugs and Natural Compounds, volume II

This Research Topic is part of a series with: Novel Targets for Chronic Inflammatory Diseases: Focus On Therapeutic Drugs and Natural Compounds Chronic inflammation is a component of many disease conditions that affect a large group of individuals worldwide, which is characterized by persistent, low-grade inflammation and is increased in the aging population. It occurs when an initiating stimulus is not removed or if the resolution process is disrupted, resulting in a state of low-grade inflammation. It is acknowledged that chronic inflammatory diseases are involved in cardiovascular diseases, endocrine disease, neurodegenerative disease, hepatic disease, pulmonary disease, gastrointestinal disease, and cancer et al., including but not limited to atherosclerosis, diabetes, multiple sclerosis, fibrosis, NAFLD, COPD, inflammatory bowel disease, autoimmune disorders(like SLE, RA), which are major causes of death worldwide. Immunity is a physiological function of the human body, which maintains health by destroying and rejecting foreign substances including antigens, damaged cells, and tumors et al. There is a close relationship between inflammation and immunity, whether they are both protective mechanisms against invasion or injury responses. Therefore, the important role of inflammatory and immune responses should be noted, it is necessary to explore novel targets and therapeutic drugs for chronic inflammatory diseases.