T In Ct M S C

University Curricula in the Marine Sciences and Related Fields

Abigail Adams

Winner of the Bancroft Prize The New York Times Book Review, Editor’s Choice American Heritage, Best of 2009 In this vivid new biography of Abigail Adams, the most illustrious woman of the founding era, Bancroft Award–winning historian Woody Holton offers a sweeping reinterpretation of Adams’s life story and of women’s roles in the creation of the republic. Using previously overlooked documents from numerous archives, Abigail Adams shows that the wife of the second president of the United States was far more charismatic and influential than historians have realized. One of the finest writers of her age, Adams passionately campaigned for women’s education, denounced sex discrimination, and matched wits not only with her brilliant husband, John, but with Thomas Jefferson and George Washington. When male Patriots ignored her famous appeal to "Remember the Ladies," she accomplished her own personal declaration of independence: Defying centuries of legislation that assigned married women’s property to their husbands, she amassed a fortune in her own name. Adams’s life story encapsulates the history of the founding era, for she defined herself in relation to the people she loved or hated (she was never neutral), a cast of characters that included her mother and sisters; Benjamin Franklin and James Lovell, her husband’s bawdy congressional colleagues; Phoebe Abdee, her father’s former slave; her financially naïve husband; and her son John Quincy. At once epic and intimate, Abigail Adams, sheds light on a complicated, fascinating woman, one of the most beloved figures of American history.

Stem Cell-Based Therapy for Lung Disease

This book presents state-of-the-art pre-clinical models and clinical applications of stem-cell-based therapies applied to different lung diseases, with a special focus on the translation of bench data into clinical studies. Starting with the assumption that abnormal lung tissue repair and regeneration has emerged as the driving force underlying pathogenesis and progression in many lung diseases, it sheds new light on the potential of stem/stromal cells as drivers of repair and sources of reparative factors in the lung. The first part of the book offers an overview of stem cell types and mechanisms involved in lung development, homeostasis, repair and regeneration, and reveals the crucial role of the extracellular matrix within the lung microenvironment. In the second part, leading experts present the latest pre-clinical evidence and clinical applications of stem-cell-based therapies in a wide variety of lung diseases, ranging from COPD and lung fibrosis to other rare lung diseases. The last section discusses stem cell delivery systems and devices, such as aerosolised spray application. This book appeals to pneumologists, stem cell and matrix biologists, as well as bioengeneers with a special interest in regenerative medicine applied to pulmonary diseases.