Survival Analysis With Python
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Survival Analysis with Python
Survival analysis uses statistics to calculate time to failure. Survival Analysis with Python takes a fresh look at this complex subject by explaining how to use the Python programming language to perform this type of analysis. As the subject itself is very mathematical and full of expressions and formulations, the book provides detailed explanations and examines practical implications. The book begins with an overview of the concepts underpinning statistical survival analysis. It then delves into Parametric models with coverage of Concept of maximum likelihood estimate (MLE) of a probability distribution parameter MLE of the survival function Common probability distributions and their analysis Analysis of exponential distribution as a survival function Analysis of Weibull distribution as a survival function Derivation of Gumbel distribution as a survival function from Weibull Non-parametric models including Kaplan–Meier (KM) estimator, a derivation of expression using MLE Fitting KM estimator with an example dataset, Python code and plotting curves Greenwood’s formula and its derivation Models with covariates explaining The concept of time shift and the accelerated failure time (AFT) model Weibull-AFT model and derivation of parameters by MLE Proportional Hazard (PH) model Cox-PH model and Breslow’s method Significance of covariates Selection of covariates The Python lifelines library is used for coding examples. By mapping theory to practical examples featuring datasets, this book is a hands-on tutorial as well as a handy reference.
An Introduction to Statistical Learning
An Introduction to Statistical Learning provides an accessible overview of the field of statistical learning, an essential toolset for making sense of the vast and complex data sets that have emerged in fields ranging from biology to finance, marketing, and astrophysics in the past twenty years. This book presents some of the most important modeling and prediction techniques, along with relevant applications. Topics include linear regression, classification, resampling methods, shrinkage approaches, tree-based methods, support vector machines, clustering, deep learning, survival analysis, multiple testing, and more. Color graphics and real-world examples are used to illustrate the methods presented. This book is targeted at statisticians and non-statisticians alike, who wish to use cutting-edge statistical learning techniques to analyze their data. Four of the authors co-wrote An Introduction to Statistical Learning, With Applications in R (ISLR), which has become a mainstay of undergraduate and graduate classrooms worldwide, as well as an important reference book for data scientists. One of the keys to its success was that each chapter contains a tutorial on implementing the analyses and methods presented in the R scientific computing environment. However, in recent years Python has become a popular language for data science, and there has been increasing demand for a Python-based alternative to ISLR. Hence, this book (ISLP) covers the same materials as ISLR but with labs implemented in Python. These labs will be useful both for Python novices, as well as experienced users.
Biostatistics with Python
Learn how to utilize biostatistics with Python for excelling in research and biomedical professions with practical exemplar projects Key Features Bridge the gap between biostatistics and life sciences with Python Work with practical exercises for real-world data analysis in biology and medicine Access a portfolio of exemplar projects in the domains of biomedicine, biotechnology, and biology Purchase of the print or Kindle book includes a free PDF eBook Book DescriptionThis book leverages the author’s decade-long experience in biostatistics and data science to simplify the practical use of biostatistics with Python. The chapters show you how to clean and describe your data effectively, setting a solid foundation for accurate analysis and proficiency in biostatistical inference to help you draw meaningful conclusions from your data through hypothesis testing and effect size analysis. The book walks you through predictive modeling to harness the power of Python to create robust predictive analytics that can drive your research and professional projects forward. You'll explore clinical biostatistics, learn how to design studies, conduct survival analysis, and synthesize evidence from multiple studies with meta-analysis – skills that are crucial for making informed decisions based on comprehensive data reviews. The concluding chapters will enhance your ability to analyze biological variables, enabling you to perform detailed and accurate data analysis for biological research. This book's unique blend of biostatistics and Python helps you find practical solutions that make complex concepts easy to grasp and apply. By the end of this biostatistics book, you’ll have moved from theoretical knowledge to practical experience, allowing you to perform biostatistical analysis confidently and accurately.What you will learn Get to grips with the basics of biostatistics and Python programming Clean and describe data using Python Familiarize yourself with hypothesis testing and effect size analysis Explore predictive modeling in biostatistics Understand clinical study design and survival analysis Gain a clear understanding of the meta-analysis of clinical research data Analyze biological variables with Python Discover practical data analysis for biological research Who this book is for This book is for life science professionals, researchers, biomedical professionals, and aspiring biostatisticians who want to integrate biostatistics into their work or research. A basic understanding of life sciences, biology, or medicine is recommended to fully benefit from this book.