Statistics In Research And Development Second Edition

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Statistical Analysis of Human Growth and Development

Statistical Analysis of Human Growth and Development is an accessible and practical guide to a wide range of basic and advanced statistical methods that are useful for studying human growth and development. Designed for nonstatisticians and statisticians new to the analysis of growth and development data, the book collects methods scattered through
Statistical Issues in Drug Development

Drug development is the process of finding and producingtherapeutically useful pharmaceuticals, turning them into safe andeffective medicine, and producing reliable information regardingthe appropriate dosage and dosing intervals. With regulatoryauthorities demanding increasingly higher standards in suchdevelopments, statistics has become an intrinsic and criticalelement in the design and conduct of drug development programmes. Statistical Issues in Drug Development presents anessential and thought provoking guide to the statistical issues andcontroversies involved in drug development. This highly readable second edition has been updated toinclude: Comprehensive coverage of the design and interpretation ofclinical trials. Expanded sections on missing data, equivalence, meta-analysisand dose finding. An examination of both Bayesian and frequentist methods. A new chapter on pharmacogenomics and expanded coverage ofpharmaco-epidemiology and pharmaco-economics. Coverage of the ICH guidelines, in particular ICH E9,Statistical Principles for Clinical Trials. It is hoped that the book will stimulate dialogue betweenstatisticians and life scientists working within the pharmaceuticalindustry. The accessible and wide-ranging coverage make itessential reading for both statisticians and non-statisticiansworking in the pharmaceutical industry, regulatory bodies andmedical research institutes. There is also much to benefitundergraduate and postgraduate students whose courses include amedical statistics component.
Statistics in Research and Development, Second Edition

Many scientists and technologists would like to carry out their own statistical analyses without reference to a professional statistician. Often, however, they have no knowledge of statistics or otherwise do not know how to apply it to research and development problems. The first edition of Statistics in Research and Development was written for these people. The second edition brings the book up-to-date. The text is divided into two parts; the first introduces basic but very important statistical techniques whilst the second part presents the modern powerful methods of data analysis that are particularly useful in modern research and development. Problems are provided at the end of each chapter with worked solutions provided at the end of the book. A problem-centered approach is used throughout and care has been taken to choose problems with which the scientist or technologist can identify. The results of the statistical analyses are reinterpreted into the language of the scientist. Mathematics is kept to a minimum and the assumptions underlying each technique are clearly explained. All the techniques introduced are powerful and proven, and commercial computer programs are available for many of them.