Spatially Variable Genes In Cancer Development Progression And Treatment Response

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Spatially Variable Genes in Cancer: Development, Progression, and Treatment Response

Spatial variable genes (SVGs) in cancer refer to genes that exhibit different expression levels or patterns across different regions or cells within a tumor. Cancer-associated fibroblasts (CAFs) are a crucial component of the tumor microenvironment (TME), playing a fundamental role in tumor progression, metastasis, and therapy response. Identifying and characterizing SVGs can reveal novel targets for cancer treatment. Combining spatial transcriptomics with other omics data can provide a more comprehensive picture of tumor biology. Spatially Variable Genes in Cancer: Development, Progression, and Treatment Response illuminates the heterogeneity within tumors, challenging the traditional one-size-fits-all approach. The chapters examine how SVGs influence tumor biology and pave the way for novel diagnostic and therapeutic approaches. Covering topics such as bioengineering, gene expression, and tumor initiation, this book is an excellent resource for academicians, researchers, students, oncologists, medical professionals, medical administrators, scientists, and more.
Cancer Exposomics and Environmental Influences on Carcinogenesis

Cancer exposomics is an emerging field seeking to understand how environmental exposures across a person's lifetime contribute to cancer development. Exposomics emphasize the role of external and internal environmental influences, including pollutants, diet, lifestyle, infections, and the microbiome, in carcinogenesis. This approach leverages advanced technologies like spectrometry, bioinformatics, and data analysis to map complex exposure-disease relationships. By uncovering the environmental causes of cancer, exposomics can inform prevention strategies, early detection, and targeted interventions, shifting treatment to proactive health protection. Cancer Exposomics and Environmental Influences on Carcinogenesis explores multi-omics and its application in the exposomics of cancer. It serves as a vital resource for researchers, bridging the gap between scientific research and practical applications in cancer prevention and treatment. This book covers topics such as biology, environmental science, and medical technology, and is a useful resource for medical and healthcare workers, oncologists, engineers, academicians, researchers, and environmental scientists.
Unveiling Technological Advancements and Interdisciplinary Solutions for Pain Care

Pain management has shifted in recent years, driven by technological advancements and an emphasis on interdisciplinary collaboration. As the understanding of pain becomes more nuanced, recognizing its physical, emotional, and psychological dimensions, healthcare professionals turn to new tools and strategies for enhanced patient outcomes. From wearable monitoring devices and AI-powered diagnostics to integrative approaches involving psychology, physiotherapy, and pharmacology, modern pain care moves beyond traditional methods. Further exploration of the evolving landscape of pain management may reveal how cutting-edge technologies and collaborative care models can reshape the understanding, assessment, and treatment of pain in diverse patient populations. Unveiling Technological Advancements and Interdisciplinary Solutions for Pain Care explores the transformative power of technological innovations, such as wearable sensors, digital tools, and data analysis in understanding unique pain patterns and developing personalized treatment plans. It examines shared decision-making practices, including the importance of building a support system through online communities, fostering emotional well-being, and living a fulfilling life despite chronic pain. This book covers topics such as acute and chronic pain, medical stigma, and personalized healthcare, and is a useful resource for medical and healthcare professionals, engineers, academicians, researchers, and scientists.