Roles And Functions Of Ros And Rns In Cellular Physiology And Pathology
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Roles and Functions of ROS and RNS in Cellular Physiology and Pathology
Our common knowledge on oxidative stress has evolved substantially over the years and has been mostly focused on the fundamental chemical reactions and the most relevant chemical species involved in the human pathophysiology of oxidative stress-associated diseases. Thus, reactive oxygen species and reactive nitrogen species (ROS and RNS) were identified as the key players initiating, mediating, and regulating the cellular and biochemical complexity of oxidative stress either as physiological (acting pro-hormetic) or as pathogenic (causing destructive vicious circle) process. The papers published in this particular Special Issue of the Cells demonstrate the impressive pathophysiological relevance of ROS and RNS in a range of contexts, including the relevance of second messengers of free radicals like 4-hydroxynonenal, allowing us to assume that even more detailed mechanisms of their positive and negative effects lie in wait, and should assist in better monitoring of the major modern diseases and the development of advanced integrative biomedicine treatments.
The Role of Reactive Oxygen Species in Human Health and Disease
Author: Prabhakar, Pranav Kumar
language: en
Publisher: IGI Global
Release Date: 2025-05-07
Reactive oxygen species (ROS) are highly reactive molecules that play a crucial role in human health, influencing a wide range of physiological processes. While ROS are essential for normal cellular functions, such as signaling, immune responses, and metabolism, their accumulation or imbalance can lead to oxidative stress, which is implicated in numerous diseases. Overproduction of ROS is associated with conditions like cardiovascular disease, cancer, neurodegenerative disorders, and diabetes. Conversely, a controlled production of ROS is vital for maintaining health and regulating cell signaling pathways. Understanding the delicate balance between ROS generation and detoxification is key to developing strategies for preventing and managing oxidative stress-related diseases, highlighting the complex role of ROS in both promoting health and contributing to disease. The Role of Reactive Oxygen Species in Human Health and Disease explores the role of ROS in human health and disease, shedding light on the often overlooked yet significant impact of ROS on health dynamics. It examines the pivotal role of reactive oxygen species in various physiological processes. This book covers topics such as medical diseases, oxidative stress, and precision medicine, and is a useful resource for medical professionals, healthcare workers, engineers, scientists, academicians, and researchers.
Fundamental and Biomedical Aspects of Redox Processes
Redox processes represent a major advancement in water treatment technology and have other applications across environmental and technological contexts. Redox processes must be studied further to ensure they are utilized appropriately. Fundamental and Biomedical Aspects of Redox Processes accumulates new knowledge regarding the essence of the oxidation-reduction processes, the justification of key mechanisms, and the discovery of new aspects of methods of controlling redox reactions. Covering key topics such as wastewater treatment, soil, natural waters, and chemistry, this reference work is ideal for industry professionals, scientists, researchers, academicians, scholars, practitioners, instructors, and students.