Robust Methods In Biostatistics


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Robust Methods in Biostatistics


Robust Methods in Biostatistics

Author: Stephane Heritier

language: en

Publisher: John Wiley & Sons

Release Date: 2009-05-11


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Robust statistics is an extension of classical statistics that specifically takes into account the concept that the underlying models used to describe data are only approximate. Its basic philosophy is to produce statistical procedures which are stable when the data do not exactly match the postulated models as it is the case for example with outliers. Robust Methods in Biostatistics proposes robust alternatives to common methods used in statistics in general and in biostatistics in particular and illustrates their use on many biomedical datasets. The methods introduced include robust estimation, testing, model selection, model check and diagnostics. They are developed for the following general classes of models: Linear regression Generalized linear models Linear mixed models Marginal longitudinal data models Cox survival analysis model The methods are introduced both at a theoretical and applied level within the framework of each general class of models, with a particular emphasis put on practical data analysis. This book is of particular use for research students,applied statisticians and practitioners in the health field interested in more stable statistical techniques. An accompanying website provides R code for computing all of the methods described, as well as for analyzing all the datasets used in the book.

Robust Nonparametric Statistical Methods


Robust Nonparametric Statistical Methods

Author: Thomas P. Hettmansperger

language: en

Publisher: Hodder Education

Release Date: 1998


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Based in ranks of the data, this book offers an alternative to the traditional least squares approach. Topics include one- and two-sample location models, linear models (including multiple regression and designed experiments), and multivariate models. Rank tests and estimates for all models are developed, including bounded influence and high breakdown methods. Emphasis is on efficiency and robustness and all methods are illustrated on data sets.

Fundamentals of Modern Statistical Methods


Fundamentals of Modern Statistical Methods

Author: Rand R. Wilcox

language: en

Publisher: Springer

Release Date: 2010-03-10


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Conventional statistical methods have a very serious flaw. They routinely miss differences among groups or associations among variables that are detected by more modern techniques, even under very small departures from normality. Hundreds of journal articles have described the reasons standard techniques can be unsatisfactory, but simple, intuitive explanations are generally unavailable. Situations arise where even highly nonsignificant results become significant when analyzed with more modern methods. Without assuming the reader has any prior training in statistics, Part I of this book describes basic statistical principles from a point of view that makes their shortcomings intuitive and easy to understand. The emphasis is on verbal and graphical descriptions of concepts. Part II describes modern methods that address the problems covered in Part I. Using data from actual studies, many examples are included to illustrate the practical problems with conventional procedures and how more modern methods can make a substantial difference in the conclusions reached in many areas of statistical research. The second edition of this book includes a number of advances and insights that have occurred since the first edition appeared. Included are new results relevant to medians, regression, measures of association, strategies for comparing dependent groups, methods for dealing with heteroscedasticity, and measures of effect size.