Recoding

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Recoding: Expansion of Decoding Rules Enriches Gene Expression

Author: John F. Atkins
language: en
Publisher: Springer Science & Business Media
Release Date: 2010-03-10
The literature on recoding is scattered, so this superb book ?lls a need by prov- ing up-to-date, comprehensive, authoritative reviews of the many kinds of recoding phenomena. Between 1961 and 1966 my colleagues and I deciphered the genetic code in Escherichia coli and showed that the genetic code is the same in E. coli, Xenopus laevis, and guinea pig tissues. These results showed that the code has been c- served during evolution and strongly suggested that the code appeared very early during biological evolution, that all forms of life on earth descended from a c- mon ancestor, and thus that all forms of life on this planet are related to one another. The problem of biological time was solved by encoding information in DNA and retrieving the information for each new generation, for it is easier to make a new organism than it is to repair an aging, malfunctioning one. Subsequently, small modi?cations of the standard genetic code were found in certain organisms and in mitochondria. Mitochondrial DNA only encodes about 10–13 proteins, so some modi?cations of the genetic code are tolerated that pr- ably would be lethal if applied to the thousands of kinds of proteins encoded by genomic DNA.
Recoded City

Recoded City examines alternative urban design, planning and architecture for the other 90%: namely the practice of participatory placemaking, a burgeoning practice that co-author Thomas Ermacora terms ‘recoding’. In combining bottom-up and top-down means of regenerating and rebalancing neighbourhoods affected by declining welfare or struck by disaster, this growing movement brings greater resilience. Recoded City sheds light on a new epoch in the relationship between cities and civil society by presenting an emerging range of collaborative solutions and distributed governance models. The authors draw on their own fresh research of global pioneers forging localist design strategies, public-realm interventions and new stakeholder dynamics. As the world becomes increasingly digital and virtual, a myriad of online tools and technological options is becoming available. These give unprecedented co-creation opportunities to communities and professionals alike, yielding the benefits of a more open – DIY – society. Because of its close engagement with people, place and local identity, the field of participatory placemaking has huge untapped potential. Responding to the challenges of the Anthropocene era, Recoded City is for decision-makers, developers and practitioners working globally to make better and more liveable cities.
R for SAS and SPSS Users

Author: Robert A. Muenchen
language: en
Publisher: Springer Science & Business Media
Release Date: 2009-03-02
While SAS and SPSS have many things in common, R is very different. My goal in writing this book is to help you translate what you know about SAS or SPSS into a working knowledge of R as quickly and easily as possible. I point out how they differ using terminology with which you are familiar, and show you which add-on packages will provide results most like those from SAS or SPSS. I provide many example programs done in SAS, SPSS, and R so that you can see how they compare topic by topic. When finished, you should be able to use R to: Read data from various types of text files and SAS/SPSS datasets. Manage your data through transformations or recodes, as well as splitting, merging and restructuring data sets. Create publication quality graphs including bar, histogram, pie, line, scatter, regression, box, error bar, and interaction plots. Perform the basic types of analyses to measure strength of association and group differences, and be able to know where to turn to cover much more complex methods.