Probabilistic Models Of Population Evolution

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Probabilistic Models of Population Evolution

This expository book presents the mathematical description of evolutionary models of populations subject to interactions (e.g. competition) within the population. The author includes both models of finite populations, and limiting models as the size of the population tends to infinity. The size of the population is described as a random function of time and of the initial population (the ancestors at time 0). The genealogical tree of such a population is given. Most models imply that the population is bound to go extinct in finite time. It is explained when the interaction is strong enough so that the extinction time remains finite, when the ancestral population at time 0 goes to infinity. The material could be used for teaching stochastic processes, together with their applications. Étienne Pardoux is Professor at Aix-Marseille University, working in the field of Stochastic Analysis, stochastic partial differential equations, and probabilistic models in evolutionary biology and population genetics. He obtained his PhD in 1975 at University of Paris-Sud.
Probability Models for DNA Sequence Evolution

Author: Rick Durrett
language: en
Publisher: Springer Science & Business Media
Release Date: 2013-03-09
Our basic question is: Given a collection of DNA sequences, what underlying forces are responsible for the observed patterns of variability? To approach this question we introduce and analyze a number of probability models: the Wright-Fisher model, the coalescent, the infinite alleles model, and the infinite sites model. We study the complications that come from nonconstant population size, recombination, population subdivision, and three forms of natural selection: directional selection, balancing selection, and background selection. These theoretical results set the stage for the investigation of various statistical tests to detect departures from "neutral evolution." The final chapter studies the evolution of whole genomes by chromosomal inversions, reciprocal translocations, and genome duplication. Throughout the book, the theory is developed in close connection with data from more than 60 experimental studies from the biology literature that illustrate the use of these results. This book is written for mathematicians and for biologists alike. We assume no previous knowledge of concepts from biology and only a basic knowledge of probability: a one semester undergraduate course and some familiarity with Markov chains and Poisson processes. Rick Durrett received his Ph.D. in operations research from Stanford University in 1976. He taught in the UCLA mathematics department before coming to Cornell in 1985. He is the author of six books and 125 research papers, and is the academic father of more than 30 Ph.D. students. His current interests are the use of probability models in genetics and ecology, and decreasing the mean and variance of his golf.
Population Dynamics: Algebraic And Probabilistic Approach

A population is a summation of all the organisms of the same group or species, which live in a particular geographical area, and have the capability of interbreeding. The main mathematical problem for a given population is to carefully examine the evolution (time dependent dynamics) of the population. The mathematical methods used in the study of this problem are based on probability theory, stochastic processes, dynamical systems, nonlinear differential and difference equations, and (non-)associative algebras.A state of a population is a distribution of probabilities of the different types of organisms in every generation. Type partition is called differentiation (for example, sex differentiation which defines a bisexual population). This book systematically describes the recently developed theory of (bisexual) population, and mainly contains results obtained since 2010.The book presents algebraic and probabilistic approaches in the theory of population dynamics. It also includes several dynamical systems of biological models such as dynamics generated by Markov processes of cubic stochastic matrices; dynamics of sex-linked population; dynamical systems generated by a gonosomal evolution operator; dynamical system and an evolution algebra of mosquito population; and ocean ecosystems.The main aim of this book is to facilitate the reader's in-depth understanding by giving a systematic review of the theory of population dynamics which has wide applications in biology, mathematics, medicine, and physics.