Preparation Function And Application Of Postbiotics

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Preparation, Function and Application of Postbiotics

An increasing number of studies on probiotics have found strong evidence that bacterial viability is not essential for imparting health benefits. It has been demonstrated in many studies that inactivated bacteria, bacterial cell components (peptidoglycans, lipoteichoic acids), or probiotic-derived metabolites (vitamins, polyphenols, bacteriocin, exopolysaccharides, short-chain fatty acids) can significantly improve host health. In 2021, the International Scientific Association for Probiotics and Prebiotics (ISAPP) convened a panel of experts specializing in nutrition, microbial physiology, gastroenterology, pediatrics, food science and microbiology to propose a useful definition of “postbiotic”, which was defined as a “preparation of inanimate microorganisms and/or their components that confers a health benefit on the host.” Postbiotics have been proven to be excellent health effectors with multiple functions, including alleviating inflammatory bowel syndrome, eradicating Helicobacter pylori residing from the stomach, abrogating the negative effects of stress, anti-inflammation, anti-bacteria, alleviating asthma, anti-infection, anti-tumor, anti-allergy, and so on. In addition to these beneficial effects listed above, postbiotics have several advantages over probiotics, including higher safety, a longer shelf life, and more sites of action (e.g., gut, skin, oral cavity, urogenital tract, or nasopharynx), which will broaden their application fields.
Probiotic Bacteria and Postbiotic Metabolites: Role in Animal and Human Health

This book covers all aspects of probiotic bacteria and their metabolites, as well as their role and significance in human and animal health. Given the role of probiotic bacterial strains in the production of short chain fatty acids, butyrate etc probiotics may be considered as an alternative approach for the prevention or treatment of intestinal dysbiosis, cancers, cardiovascular diseases, hypertensions. Additionally, the significance of probiotics added in aquaculture systems for improving health, performance and growth of aquatic organisms has been highlighted. In this book, the multi-functional role of probiotics and their post-biotic metabolites in improving overall health status of man and animals, is discussed. It is a comprehensive compilation useful for researchers, academics, veterinarians and students in the field of microbiology, food technology and biotechnology.
Postbiotics

Author: Dhanasekaran Dharumadurai
language: en
Publisher: Elsevier
Release Date: 2024-10-09
Postbiotics: Health and Industry provides a detailed overview on the fundamentals, biological and therapeutic properties, safety, and application of postbiotics in health and industry. Sections cover the fundamentals of postbiotics, which include insights on probiotic microorganisms, postbiotics, and host–microbe interaction, analysis, and characterization of postbiotics. The book goes on to delve into the different types of postbiotics and their mechanisms. Remaining sections explore various health, pharmaceutical, and industrial applications of postbiotics. - Provides an overview on the separation, characterization, and identification of postbiotics from probiotic microbes - Includes classes of postbiotics and their mechanisms of action - Discusses the safety of postbiotics in humans and animals and the use of multiomics to understand the effect of postbiotics on human physiology - Analyzes existing regulatory framework for postbiotics