Polarized Light In Biomedical Imaging And Sensing
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Polarized Light in Biomedical Imaging and Sensing
Author: Jessica C. Ramella-Roman
language: en
Publisher: Springer Nature
Release Date: 2022-11-14
This book focuses on biomedical applications of polarized light, covering instrumentation and modeling specific to the field. This will be the first book, written by leading researchers in the field, to tackle this important topic. Readers will learn the fundamentals of polarized light transport and how to develop instrumentation for clinical and preclinical studies. They will also become familiar with the latest advancement in data analysis and image processing for a variety of medical applications. The book is dedicated specifically to the biomedical community, including scientists, engineers, and physicians working on the development of instrumentation for clinical and preclinical use. Emphasizes biomedical imaging and sensing; Describes new computational approaches with examples; Provides detailed descriptions of novel instrumentation.
Optical Polarimetric Modalities for Biomedical Research
This book focuses on polarization microscopy, a powerful optical tool used to study anisotropic properties in biomolecules, and its enormous potential to improve diagnostic tools for various biomedical research. The interaction of polarized light with normal and abnormal regions of tissue reveals structural information associated with its pathological condition. Diagnosis using conventional microscopy can be time-consuming, as pathologists require an hour to freeze and stain tissue slices from suspected patients. In comparison, polarization microscopy more quickly distinguishes abnormal tissue and provides better microstructural information of samples, even in the absence of staining. This book provides a basic understanding of the properties of polarized light, a description of the polarization microscope, and a mathematical formalism of Mueller matrix polarimetry. The authors discuss various advanced linear and nonlinear optical techniques such as optical coherence tomography (OCT), reflectance and transmission spectroscopy, fluorescence, multiphoton excitation, second harmonic generation, Raman microscopy, and more. They explore the exciting potential of integrating polarimetry with these techniques for possible applications in different areas of biomedical research, as well as the associated challenges. Including the most recent developments on the topic, this book serves as a modern guide to polarization microscopy and advancements in its use in biomedical research.
Nanoscale Sensors and their Applications in Biomedical Imaging
The book offers a comprehensive exploration of cutting-edge nano-sensor technologies and their critical role in the field of biomedicine. This book covers a diverse range of topics, from fluorescence-based nanosensors that detect and quantify nanovesicles at the nanoscale to the recent advances in nano biosensors for agriculture and health applications. It provides valuable insights into the green synthesis of silver nanoparticles and their biomedical applications, highlighting eco-friendly approaches to nanomaterial production. The use of FRET-based tools for real-time quantification of vitamins and bioimaging is also extensively discussed, presenting innovative techniques for analysis. The book further delves into the potential of nanosensors in medicine, exploring the characteristic features that make them promising candidates for various medical applications. It also covers the application of fluorescent biosensors for intracellular signalling analysis, paving the way for understanding complex cellular processes. The book also discusses the use of nanosensors for monitoring blood clotting disorders, offering new possibilities for diagnostic and therapeutic interventions. It also presents fluorescent probes for detecting gas transmitters, such as H2S, CO, and NO, which have significant implications in the field of gas sensing and medical research. It serves as a valuable resource for researchers, scientists, and professionals in the fields of nanotechnology, biotechnology, and medicine, offering ground-breaking insights into the rapidly evolving world of nano sensors and their significant impact on healthcare and diagnostics.