Paper Based Diagnostics
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Paper-based Diagnostics
This book explores the status of paper-based diagnostic solutions, or Microfluidics 2.0. The contributors explore: how paper-based tests can be widely distributed and utilized by semi-skilled personnel; how close to commercial applications the technology has become, and what is still required to make paper-based diagnostics the game-changer it can be. The technology is examined through the lens of the World Health Organization’s ASSURED criteria for low-resource countries (Affordable, Sensitive, Specific, User-friendly, Rapid and robust, Equipment-free, and Deliverable to end-users). Its applications have to include: health technology, environmental technology, food safety, and more. This book is appropriate for researchers in these areas, as well as those interested in microfluidics, and includes chapters dedicated to principles such as theory of flow and surface treatments; components such as biomarkers and detection; and current methods of manufacturing. Discusses how paper-based diagnostics can be used in developing countries by comparing current diagnostic tests with the World Health Organization's ASSURED criteria Examines how paper-based diagnostics could be integrated with other technologies, such as printed electronics, and the Internet of Things. Outlines how semi-skilled personnel across a variety of fields can implement paper-based diagnostics
Applications of Microfluidic Systems in Biology and Medicine
This book is the second edition of the one originally published in 2016, which focused on state-of-the-art microfluidic research in medical and biological applications. Similar to the first edition, beginners in the field —undergraduates, engineers, biologists, medical and pharmaceutical researchers—will easily learn to understand microfluidic-based medical and biological applications. Because a wide range of topics is summarized here, it also helps experts to learn more about fields outside their own specialties. In this second edition, significant revisions have been made to chapters covering technologies that have seen major advancements, such as acoustofluidics, protein crystallography, organ-on-a-chip systems, nanopore sensing, and paper-based microfluidics. In addition, the chapters on cancer diagnosis using exosomes and single-cell sequencing using droplet microfluidics, which are attracting attention as new technologies, have been newly added. Readers will be convinced that microfluidic devices have great potential for medical and biological applications.
Biosensor Based Advanced Cancer Diagnostics
Early diagnosis of cancer and other non-oncological disorders gives a significant advantage for curing the disease and improving patient's life expectancy. Recent advances in biosensor-based techniques which are designed for specific biomarkers can be exploited for early diagnosis of diseases. Biosensor Based Advanced Cancer Diagnostics covers all available biosensor-based approaches and comprehensive technologies; along with their application in diagnosis, prognosis and therapeutic management of various oncological disorders. Besides this, current challenges and future aspects of these diagnostic approaches have also been discussed. This book offers a view of recent advances and is also helpful for designing new biosensor-based technologies in the field of medical science, engineering and biomedical technology. Biosensor Based Advanced Cancer Diagnostics helps biomedical engineers, researchers, molecular biologists, oncologists and clinicians with the development of point of care devices for disease diagnostics and prognostics. It also provides information on developing user friendly, sensitive, stable, accurate, low cost and minimally invasive modalities which can be adopted from lab to clinics. This book covers in-depth knowledge of disease biomarkers that can be exploited for designing and development of a range of biosensors. The editors have summarized the potential cancer biomarkers and methodology for their detection, plus transferring the developed system to clinical application by miniaturization and required integration with microfluidic systems. Covers design and development of advanced platforms for rapid diagnosis of cancerous biomarkers Takes a multidisciplinary approach to sensitive transducers development, nano-enabled advanced imaging, miniaturized analytical systems, and device packaging for point-of-care applications Offers an insight into how to develop cost-effective diagnostics for early detection of cancer