Pairwise Comparisons Using Wilcoxon Rank Sum Exact Test
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A Conceptual Guide to Statistics Using SPSS
This book helps students develop a conceptual understanding of a variety of statistical tests by linking the statistics with the computational steps and output from SPSS. Learning how statistical ideas map onto computation in SPSS will help students build a better understanding of both. For example, seeing exactly how the concept of variance is used in SPSS-how it is converted into a number based on real data, which other concepts it is associated with, and where it appears in various statistical tests-will not only help students understand how to use statistical tests in SPSS and how to interpret their output, but will also teach them about the concept of variance itself. Each chapter begins with a student-friendly explanation of the concept behind each statistical test and how the test relates to that concept. The authors then walk through the steps to compute the test in SPSS and the output, pointing out wherever possible how the SPSS procedure and output connects back to the conceptual underpinnings of the test. Each of the steps is accompanied by annotated screen shots from SPSS, and relevant components of output are highlighted in both the text and in the figures. Sections explain the conceptual machinery underlying the statistical tests. In contrast to merely presenting the equations for computing the statistic, these sections describe the idea behind each test in plain language and help students make the connection between the ideas and SPSS procedures. These include extensive treatment of custom hypothesis testing in ANOVA, MANOVA, ANCOVA, and regression, and an entire chapter on the advanced matrix algebra functions available only through syntax in SPSS. The book will be appropriate for both advanced undergraduate and graduate level courses in statistics.
Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences
Author: Paul J. Mitchell
language: en
Publisher: John Wiley & Sons
Release Date: 2022-04-18
Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences A practical guide to the use of basic principles of experimental design and statistical analysis in pharmacology Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences provides clear instructions on applying statistical analysis techniques to pharmacological data. Written by an experimental pharmacologist with decades of experience teaching statistics and designing preclinical experiments, this reader-friendly volume explains the variety of statistical tests that researchers require to analyze data and draw correct conclusions. Detailed, yet accessible, chapters explain how to determine the appropriate statistical tool for a particular type of data, run the statistical test, and analyze and interpret the results. By first introducing basic principles of experimental design and statistical analysis, the author then guides readers through descriptive and inferential statistics, analysis of variance, correlation and regression analysis, general linear modelling, and more. Lastly, throughout the textbook are numerous examples from molecular, cellular, in vitro, and in vivo pharmacology which highlight the importance of rigorous statistical analysis in real-world pharmacological and biomedical research. This textbook also: Describes the rigorous statistical approach needed for publication in scientific journals Covers a wide range of statistical concepts and methods, such as standard normal distribution, data confidence intervals, and post hoc and a priori analysis Discusses practical aspects of data collection, identification, and presentation Features images of the output from common statistical packages, including GraphPad Prism, Invivo Stat, MiniTab and SPSS Experimental Design and Statistical Analysis for Pharmacology and the Biomedical Sciences is an invaluable reference and guide for undergraduate and graduate students, post-doctoral researchers, and lecturers in pharmacology and allied subjects in the life sciences.
Bioinformatic and Statistical Analysis of Microbiome Data
This unique book addresses the bioinformatic and statistical modelling and also the analysis of microbiome data using cutting-edge QIIME 2 and R software. It covers core analysis topics in both bioinformatics and statistics, which provides a complete workflow for microbiome data analysis: from raw sequencing reads to community analysis and statistical hypothesis testing. It includes real-world data from the authors’ research and from the public domain, and discusses the implementation of QIIME 2 and R for data analysis step-by-step. The data as well as QIIME 2 and R computer programs are publicly available, allowing readers to replicate the model development and data analysis presented in each chapter so that these new methods can be readily applied in their own research. Bioinformatic and Statistical Analysis of Microbiome Data is an ideal book for advanced graduate students and researchers in the clinical, biomedical, agricultural, and environmental fields, as well as those studying bioinformatics, statistics, and big data analysis.