Ostnatal Sex
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Kisspeptin Signaling in Reproductive Biology
Author: Alexander S. Kauffman
language: en
Publisher: Springer Science & Business Media
Release Date: 2013-04-02
Kisspeptin has been shown to be both necessary and sufficient for activation of the reproductive axis, during puberty and later in adulthood. This makes kisspeptin a fundamental component of the reproductive axis. Kisspeptin has been deemed the single most potent stimulator of GnRH neurons yet known. The importance of kisspeptin has been documented in humans as well as non-human animal models, ranging from monkeys, sheep, and rodents to numerous fish species, thus signifying a highly conserved nature of its reproductive function. Importantly, kisspeptin neurons seem to mediate many of the regulatory effects of other signals, whether they are metabolic, circadian, hormonal, or stress. This places kisspeptin neurons in a unique position to be key nodal points and conduits for conveying numerous endogenous and exogenous signals to the reproductive axis.
Routledge Handbook of Asian Demography
Home to close to 60 per cent of the world’s population, Asia is the largest and by far the most populous continent. It is also extremely diverse, physically and culturally. Asian countries and regions have their own distinctive histories, cultural traditions, religious beliefs and political systems, and they have often pursued different routes to development. Asian populations also present a striking array of demographic characteristics and stages of demographic transition. This handbook is the first to provide a comprehensive study of population change across the whole of Asia. Comprising 28 chapters by more than 40 international experts this handbook examines demographic transitions on the continent, their considerable variations, their causes and consequences, and their relationships with a wide range of social, economic, political and cultural processes. Major topics covered include: population studies and sources of demographic data; historical demography; family planning and fertility decline; sex preferences; mortality changes; causes of death; HIV/AIDS; population distribution and migration; urbanization; marriage and family; human capital and labour force; population ageing; demographic dividends; political demography; population and environment; and Asia’s demographic future. This handbook provides an authoritative and comprehensive reference for researchers, policymakers, academics, students and anyone who is interested in population change in Asia and the world.