Open The Cage Of Binding
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Diarylethene Molecular Photoswitches
A comprehensive review to the synthesis, properties, and applications of diarylethene-based molecular photoswitches Diarylethene Molecular Photoswitches: Concept and Functionalities provides the fundamental concepts of molecular photoswitches and includes information on how the bistable photoswitches of diarylethenes modulate the functions of materials and biological activities. Written by Masahiro Irie (the inventor of photochromic diarylethene compound), the book explores the reaction mechanism, photoswitching performance, photoswitchable crystals, and the myriad applications of diarylethenes based photoswitches. This book offers academics, chemists, and engineers an essential resource for understanding the molecular photoswitches and provides a guide to the development of new photoresponsive materials. The author explores the applications based on diarylethene and its dirivatives to Field-Effect Transistors, Metal-Organic Frameworks including nanoparticles, super-resolution fluorescence microscopies, drug release, and self-healing materials. This important book: * Offers a guide to diarylethene derivatives, the most widely studied compounds worldwide among the photochromic compounds * Includes the basic concepts of molecular photoswitches * Explores the myraid applications grounded in diarylethene and its derivatives * Presents an authortative text from the inventor of the photochromic diarylethene compound Written for materials scientists, organic, polymer, and physical chemists, and electronics engineers, Diarylethene Molecular Photoswitches offers an introduction to the topic and includes recent developments in the field.
Density Functional Theory
Author: Ponnadurai Ramasami
language: en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date: 2018-12-17
DFT methods are widely used in a broad range of disciplines to investigate many body systems. This book provides an overview on contemporary applications of the Density Functional Theory in various fields as computational chemistry, physics or engineering.
Calming the Brain
This book covers the entire field of research in the area of minor tranquillizers and its application to current clinical practice in the treatment of anxiety and insomnia. These drugs are principally the benzodiazepines and related drugs with a similar mechanism of action, such as zolpidem and zopiclone. The molecular mechanism of action of benzodiazepines is described, focussing on the interaction of these drugs with the different isoform of the GABAA^O >receptor, and the consequences of this for brain function. Recent advances in this knowledge have provided a framework for defining the physiochemical nature of the interaction between such drugs and their receptor protein, and thus pave the way for the design of new anxiolytic and hypnotic drugs. The animal models available for evaluating the potential of such new therapeutic agents in the treatment of anxiety and insomnia are discussed. Furthermore, understanding of the physiological regulation of the GABAA receptor may provide insights into the aetiopathology of these diseases. The clinical use of benzodiazepines and related drugs in the treatment of anxiety, insomnia, epilepsy and as anaesthetics are explored. The advantages and limitations of such treatments are discussed, and the impact of drugs evaluated. A chapter is devoted to the issue of independence, the clinical pertinence of tolerence and dependence, and evaluates treatment options that may minimise the risk of dependence.