Oecd Guidelines For The Testing Of Chemicals Section 1 Test No 120 Solution Extraction Behaviour Of Polymers In Water
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OECD Guidelines for the Testing of Chemicals, Section 1 Test No. 120: Solution/Extraction Behaviour of Polymers in Water
This Test Guideline describes a method to analyse the solution/extraction behaviour of polymers in water, which uses the flask method with modifications. Three samples of 10 g of particles of the test substance are weighed into each of three vessels ...
Introduction to Toxicological Screening Methods and Good Laboratory Practice
Author: Saravana Babu Chidambaram
language: en
Publisher: Springer Nature
Release Date: 2022-02-11
This book focuses on the principles, methods, and interpretation involved in establishing the safety, risk, and hazard assessment of small molecules. It presents the regulatory requirements for risk and hazard identification as per the guidelines of the Organization for Economic Cooperation and Development (OECD), Paris, and the International Council for Harmonisation (ICH) of Technical Requirements for Pharmaceuticals for Human Use ICH and Schedule ‘Y’, India. It serves as reference material for undergraduate and postgraduate pharmacy degree students as well as senior researchers to learn about the principles, methods, and interpretations of systemic dosage (acute and repeated dose) and genotoxicity (in vitro and in vivo), special toxicological investigations such as reproductive and developmental toxicology, carcinogenicity, and toxicokinetics using animal models or in vitro methods, as applicable. This book is the first of its kind in providing information on the principles and methods of implementation of Good Laboratory Practice based on the guidelines of OECD. It includes detailed chapters about the regulatory requirements and guidelines in pharmaceutical products and agrochemicals. It also describes the infrastructure needed for preclinical studies, including in vivo and in vitro facilities.
OECD Guidelines for the Testing of Chemicals, Section 1 Test No. 106: Adsorption -- Desorption Using a Batch Equilibrium Method
This Test Guideline is aimed at estimating the adsorption/desorption behaviour of a chemical on different soil types. The goal is to obtain a sorption value which can be used to predict partitioning under a variety of environmental conditions; to ...