Neuroimaging Workflow Design And Data Mining
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Neuroimaging Workflow Design and Data-Mining
With the increasing number of neuroimaging studies appearing yearly in the literature, the need to consider the synthesis of the underlying data into new knowledge and research directions has never been more important. The development of large-scale databases and grid-enabled computing has laid the groundwork for mining these rich datasets beyond the scope of their initial collection. Additionally, meta-analyses of the summary results contained in published research articles have provided a powerful way to explore hidden trends in the neuroscience literature. In each case, the processing of data requires a careful consideration of the individual processing steps involved and how they can be assembled into reliable workflows. In results from published studies, the manner in which data were processed may influence meta-analytic results which can have implications on clinical interpretation. Several efforts now exist that provide tools for use in the construction of data processing workflows. However, careful thought must be given to ensuring appropriate, efficient, optimal, and replicable processing. The results obtained from data-mining and meta-analysis must tell a story about a collection of existing data. Also they must suggest novel and testable hypotheses for further investigation with implications for understanding of the brain in health and disease. Where they do, these new results and interpretations often provide fresh insights into the data that extend beyond the rationale for their original collection. In this volume, we have asked leaders in the field of neuroimaging data mining and meta-analysis to provide their thoughts on methods for efficient workflow design, interoperability with large-scale databases, and to discuss their work in exploring the richness of brain imaging data as well as the literature of published research results.
Handbook of Neuroimaging Data Analysis
This book explores various state-of-the-art aspects behind the statistical analysis of neuroimaging data. It examines the development of novel statistical approaches to model brain data. Designed for researchers in statistics, biostatistics, computer science, cognitive science, computer engineering, biomedical engineering, applied mathematics, physics, and radiology, the book can also be used as a textbook for graduate-level courses in statistics and biostatistics or as a self-study reference for Ph.D. students in statistics, biostatistics, psychology, neuroscience, and computer science.
Recent Advances and the Future Generation of Neuroinformatics Infrastructure
The huge volume of multi-modal neuroimaging data across different neuroscience communities has posed a daunting challenge to traditional methods of data sharing, data archiving, data processing and data analysis. Neuroinformatics plays a crucial role in creating advanced methodologies and tools for the handling of varied and heterogeneous datasets in order to better understand the structure and function of the brain. These tools and methodologies not only enhance data collection, analysis, integration, interpretation, modeling, and dissemination of data, but also promote data sharing and collaboration. This Neuroinformatics Research Topic aims to summarize the state-of-art of the current achievements and explores the directions for the future generation of neuroinformatics infrastructure. The publications present solutions for data archiving, data processing and workflow, data mining, and system integration methodologies. Some of the systems presented are large in scale, geographically distributed, and already have a well-established user community. Some discuss opportunities and methodologies that facilitate large-scale parallel data processing tasks under a heterogeneous computational environment. We wish to stimulate on-going discussions at the level of the neuroinformatics infrastructure including the common challenges, new technologies of maximum benefit, key features of next generation infrastructure, etc. We have asked leading research groups from different research areas of neuroscience/neuroimaging to provide their thoughts on the development of a state of the art and highly-efficient neuroinformatics infrastructure. Such discussions will inspire and help guide the development of a state of the art, highly-efficient neuroinformatics infrastructure.