Na Channels From Phyla To Function
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Na Channels from Phyla to Function
Na Channels from Phyla to Function, the latest volume in the Current Topics in Membranes series, is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. This volume offers an up-to-date presentation of the current knowledge in the field of Na Channels. Written by leading experts in the field of Na Channels Contains original material, both textual and illustrative, that make it a very relevant reference Presented in a very comprehensive manner Both researchers in the field and general readers will find this book relevant and up-to-date with regard to its information
Voltage-gated Sodium Channels: Structure, Function and Channelopathies
This book provides a timely state-of-the-art overview of voltage-gated sodium channels, their structure-function, their pharmacology and related diseases. Among the topics discussed are the structural basis of Na+ channel function, methodological advances in the study of Na+ channels, their pathophysiology and drugs and toxins interactions with these channels and their associated channelopathies.
Toxins and Signal Transduction
Of the multitude of toxins known and the enormous variety of effects they cause, of particular interest are those that influence signal transduction. Intercellular communication by chemical signals is essential for the functioning of multicellular organisms. Many toxins exert their biological effects by interfering with the signal transduction initiated by these chemicals (hormones, transmitters, growth factors, and other mediators). Up-to-date information is provided by outstanding experts, who discuss the molecular mechanisms involved in the action of many toxins, as well as the use of toxins as informative tools with which to study signal transduction and their potential therapeutic usage. This volume contains useful information for the experimentalist interested in toxins or in signal transduction, as well as for the reader interested in gaining a comprehensive overview of the field. The Cellular and Molecular Mechanisms of Toxin Action series will include monographs on signal transduction, secretory systems, cytoskeleton, selective neurotoxicity of natural, recombinant and chimeric toxins giving a broader emphasis on the mechanism of action, structure-function relationship, and use of toxins as research tools and their therapeutic applications.