N P Singh
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Arid Legumes for Sustainable Agriculture and Trade (Vol. 1)
The volume contents aspects as crops i.e. Clusterbean, Mothbean, Cowpea, Horsegram, Mungbean, Rice bean, Indian bean, Winged bean and other minor pulses grown in arid and semi-arid regions.
Technologies for Detection of DNA Damage and Mutations
Author: G.P. Pfeifer
language: en
Publisher: Springer Science & Business Media
Release Date: 2013-11-11
Man-made carcinogens, natural genotoxic agents in the environment, as well as ionizing and ultraviolet radiation can damage DNA and are a constant threat to genome integrity. Throughout the evolution oflife, complex DNA repair systems have developed in all living organisms to cope with this damage. Unrepaired DNA lesions can promote genetic alterations (mutations) that may be linked to an altered phenotype, and, if growth-controlling genes are involved, these mutations can lead to cell transformation and the development of malignant tumors. Proto oncogenes and tumor suppressor genes may be critical targets for DNA damaging agents. In a number of animal model systems, correlations between exposure to a carcinogen, tumor develop ment, and genetic changes in tumor DNA have been established. To understand mutagenesis processes in more detail at the molecular level, we need to know the type and frequency of DNA adducts within cells, their distribution along genes and specific DNA sequences, as well as the rates at which they are repaired. We also need to know what types of mutations are produced and which gene positions are most prone to mutagenesis. This book provides a collection of techniques that are useful in mutagenesis research. The book is divided into three parts. In Part I, methods for DNA damage and repair analysis are provided.
Textbook of Family Medicine
Author: Arulrhaj
language: en
Publisher: Wolters kluwer india Pvt Ltd
Release Date: 2017-01-01
Textbook of Family Medicine, 3/e has been thoroughly revised and updated as per the requirement of general practitioners. Chapters contributed from a number of national and international experts in their respective fields makes this an authoritative text. The chapters have been thoroughly revised not only to incorporate symptomatic approach and management at primary care level but also the advanced treatment options available in tertiary care centres. With its contemporary approach and lucid presentation, the text would be of immense value to the general practitioners as well as students pursuing courses in Family medicine.