Mimicking The Extracellular Matrix

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Mimicking the Extracellular Matrix

Author: Gregory A Hudalla
language: en
Publisher: Royal Society of Chemistry
Release Date: 2019-03-15
The extracellular matrix (ECM) is the focus of much interest in biology and bioengineering. Increasing understanding of the influence of the ECM on cell behaviour has led to the exciting possibilities of tissue engineering. Aside from new therapeutic tools, understanding the ECM is of course fundamental to basic cell biology research. Mimicking the Extracellular Matrix approaches this topic from both basic science and practical engineering perspectives. Seven topics are approached each in a pair of chapters, one with a biological approach and its partner with a bioengineering approach. Topics include the mechanical properties of the ECM, which outlines current knowledge of the ECM physical structure and reviewing state-of-the-art strategies to mimic its native microenvironments. The organisational characteristics of the ECM form the focus of another pair of chapters, where the collagen triple helix is discussed, followed by a review of advances in artificial reproduction of well-ordered systems using self-assembling peptides, or peptide amphiphiles. The balanced approach of this text gives it a broad appeal to those interested in the ECM from a range of backgrounds and disciplines. Suitable for undergraduates, postgraduates, and academics, this text aims to unify the current knowledge of ECM biology and matrix-mimicking biomaterials.
Mimicking Nature

Author: Ashokan Kannarath
language: en
Publisher: Partridge Publishing
Release Date: 2014-01-22
This book is specially designed to get a basic idea about biomimicry as a solution for sustainable development, how animal and plant models become an ideal natural teacher to construct and design modern mans requirements without causing pollution. This book has nine chapters. The first section is devoted for introduction, the second for sustainable development, the third one for inspiration derived from plants (twenty-four examples), fourth one for inspiration derived from animals (thirty-five examples). The fifth chapter is devoted for research in biomimicry, and the sixth chapter is for development in biomimicry at the molecular level. The seventh one is for modern city planning by mimicking nature, with special reference to Lavasa, the first biomimicry town planning in India. The eighth chapter is for explanation of some case studies in biomimicry, and the last chapter is to inform the reader about some access point in biomimicry resources, followed by further study, and the last section is an index of the contents.
Mimicked Tissue Engineering Scaffolds for Maxillofacial and Articular Cartilage Surgery

This book outlines the latest research on the design and fabrication of the biomaterials used in mimicked scaffolds for tissue engineering for maxillofacial and orthopedic applications. The book is written based on integration and optimized concepts of 3 main parts 1) principle of tissue engineering; 2) mimicking of structure and function of scaffolds which is similar to extracellular matrix (ECM); and 3) mimicked scaffolds for tissue engineering in maxillofacial and orthopedic surgery. The content of this book which is interdisciplinary in nature caters to medical product designers, materials scientists and engineers, biologists, and surgeons who have interest in the field of bone tissue engineering.