Microsystems For Enhanced Control Of Cell Behavior
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Microsystems for Enhanced Control of Cell Behavior
This handbook focuses on the entire development process of biomedical microsystems that promote special interactions with cells. Fundamentals of cell biology and mechanobiology are described as necessary preparatory input for design tasks. Advanced design, simulation, and micro/nanomanufacturing resources, whose combined use enables the development of biomedical microsystems capable of interacting at a cellular level, are covered in depth. A detailed series of chapters is then devoted to applications based on microsystems that offer enhanced cellular control, including microfluidic devices for diagnosis and therapy, cell-based sensors and actuators (smart biodevices), microstructured prostheses for improvement of biocompatibility, microstructured and microtextured cell culture matrices for promotion of cell growth and differentiation, electrophoretic microsystems for study of cell mechanics, microstructured and microtextured biodevices for study of cell adhesion and dynamics, and biomimetic microsystems (including organs-on-chips), among others. Challenges relating to the development of reliable in vitro biomimetic microsystems, the design and manufacture of complex geometries, and biofabrication are also discussed.
3D Bioprinting in Regenerative Engineering
Regenerative engineering is the convergence of developmental biology, stem cell science and engineering, materials science, and clinical translation to provide tissue patches or constructs for diseased or damaged organs. Various methods have been introduced to create tissue constructs with clinically relevant dimensions. Among such methods, 3D bioprinting provides the versatility, speed and control over location and dimensions of the deposited structures. Three-dimensional bioprinting has leveraged the momentum in printing and tissue engineering technologies and has emerged as a versatile method of fabricating tissue blocks and patches. The flexibility of the system lies in the fact that numerous biomaterials encapsulated with living cells can be printed. This book contains an extensive collection of papers by world-renowned experts in 3D bioprinting. In addition to providing entry-level knowledge about bioprinting, the authors delve into the latest advances in this technology. Furthermore, details are included about the different technologies used in bioprinting. In addition to the equipment for bioprinting, the book also describes the different biomaterials and cells used in these approaches. This text: Presents the principles and applications of bioprinting Discusses bioinks for 3D printing Explores applications of extrusion bioprinting, including past, present, and future challenges Includes discussion on 4D Bioprinting in terms of mechanisms and applications
Microsystem Dynamics: Unveiling Complex Interactions
Author: Pasquale De Marco
language: en
Publisher: Pasquale De Marco
Release Date: 2025-07-20
Embark on a journey into the fascinating world of microsystems, where intricate interactions and phenomena unfold at the micro and nanoscales. This comprehensive book delves into the fundamental concepts, diverse applications, and challenges associated with these remarkable technologies. Microsystems encompass a wide spectrum of disciplines, including microelectronics, micromechanics, microfluidics, and bioengineering. They find applications in numerous fields, revolutionizing industries and transforming everyday life. From miniaturized sensors and actuators to energy harvesting and communication systems, microsystems offer unprecedented control and manipulation of matter, energy, and information at the microscale. The book begins by exploring the fundamental principles underlying microsystem dynamics, revealing the complex and nonlinear behaviors that arise from the interplay of physics, engineering, and biology. It then delves into the fabrication techniques used to create these intricate structures, highlighting the challenges and opportunities associated with miniaturization. Microsensors and microactuators are key components of microsystems, enabling the transduction of physical, chemical, and biological signals into electrical or mechanical outputs. The book provides a detailed overview of these devices, discussing their principles of operation, design considerations, and applications in various fields. Energy harvesting microsystems harness energy from various sources, such as solar, mechanical, thermal, and chemical, to power devices and systems. The book examines the different technologies used for energy harvesting, highlighting their advantages and limitations. It also explores the challenges and opportunities associated with integrating energy harvesting capabilities into microsystems. Communication and networking microsystems enable data transmission and information exchange among devices and systems at the microscale. The book discusses various communication technologies, including wireless communication, optical communication, sensor networks, and molecular communication. It also explores the challenges and opportunities associated with establishing interconnectivity and coordination among microsystem components. Microsystems have revolutionized healthcare, enabling minimally invasive procedures, targeted drug delivery, real-time monitoring, and personalized healthcare solutions. The book provides an overview of microsystems for healthcare applications, including microfluidic devices, biosensors, implantable devices, and tissue engineering scaffolds. It also highlights the challenges and opportunities associated with integrating microsystems into healthcare systems. Microsystems for environmental monitoring play a crucial role in safeguarding our planet. The book discusses the use of microsystems for air, water, and soil quality monitoring, as well as for tracking environmental parameters. It also explores the challenges and opportunities associated with developing and deploying microsystems for environmental monitoring applications. If you like this book, write a review!