Microfluidics Aided Technologies
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Microfluidics-Aided Technologies
Microfluidics-Aided Technologies: Platforms for Next Generation Biological Applications aims to provide comprehensive information of microfluidic technologies, their development and biomedical applications. The book provides the fundamentals of microfluidics and addresses the advances and challenges of microfluidic platforms for diagnostics, biological assays, cellular analysis, and drug delivery. Sections introduce micro-scale flow enabled systems, followed by discussions on applications in diagnostics, prognostics, and cellular analysis in the second and third section. The fourth section focuses on breakthroughs in microfluidics like 3D bioprinting, tissue-on-chip, organ-on-chip, and organism-on-chip. The last section provides insights on microfluidics and the study of plants and microbes. This book offers researchers an interdisciplinary perspective towards biological problems. It is a resource for advanced undergraduate, graduate students, researchers and industry scientists interested in the emergence of advance techniques and next generation microfluidics-aided technologies for applications in the biomedical and medical research. - Discusses the development of advanced techniques and methods for the diagnosis and treatment of various diseases - Discusses experimental approaches that facilitate the study of various aspects of life sciences - Presents biomaterial design strategies and recent breakthroughs for organ-on chip and organism on chip platforms - Summarize various polymers, techniques and types of microfluidic devices
Computer-Aided Design of Microfluidic Very Large Scale Integration (mVLSI) Biochips
This book provides a comprehensive overview of flow-based, microfluidic VLSI. The authors describe and solve in a comprehensive and holistic manner practical challenges such as control synthesis, wash optimization, design for testability, and diagnosis of modern flow-based microfluidic biochips. They introduce practical solutions, based on rigorous optimization and formal models. The technical contributions presented in this book will not only shorten the product development cycle, but also accelerate the adoption and further development of modern flow-based microfluidic biochips, by facilitating the full exploitation of design complexities that are possible with current fabrication techniques.
Digital Microfluidic Biochips
Digital Microfluidic Biochips focuses on the automated design and production of microfluidic-based biochips for large-scale bioassays and safety-critical applications. Bridging areas of electronic design automation with microfluidic biochip research, the authors present a system-level design automation framework that addresses key issues in the design, analysis, and testing of digital microfluidic biochips. The book describes a new generation of microfluidic biochips with more complex designs that offer dynamic reconfigurability, system scalability, system integration, and defect tolerance. Part I describes a unified design methodology that targets design optimization under resource constraints. Part II investigates cost-effective testing techniques for digital microfluidic biochips that include test resource optimization and fault detection while running normal bioassays. Part III focuses on different reconfiguration-based defect tolerance techniques designed to increase the yield and dependability of digital microfluidic biochips. Expanding upon results from ongoing research on CAD for biochips at Duke University, this book presents new design methodologies that address some of the limitations in current full-custom design techniques. Digital Microfluidic Biochips is an essential resource for achieving the integration of microfluidic components in the next generation of system-on-chip and system-in-package designs.