Microbial Pathogenomics


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Microbial Pathogenomics


Microbial Pathogenomics

Author: H. de Reuse

language: en

Publisher: Karger Medical and Scientific Publishers

Release Date: 2009-08-27


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Microbial Pathogenomics' contains a unique collection of reviews demonstrating how genomics has revolutionized our understanding of virulence, host-adaptation strategies and the evolution of bacterial pathogens. Current technologies - computational tools and functional approaches to genome analysis - are carefully documented and clearly illustrated. These include visualization tools for genome comparison, databases, in silico metabolic reconstructions and function prediction as well as interactomics for the study of protein-protein interactions. The concepts of pan-genomics and reverse vaccinology are introduced as strategies when addressing the challenge presented by bacterial diversity in the prevention and treatment of infectious diseases. The authors explore individual bacterial pathogens and discuss the mechanisms that have contributed to their evolutionary success. Special cases of host adaptation, for example, are illustrated by Helicobacter pylori and 'Mycobacterium tuberculosis' which are human-specific and highly persistent; further bacteria discussed include 'Escherichia coli, Campylobacter, Pseudomonas, Legionella, Bartonella, Burkholderia' and 'Staphylococcus'. 'Microbial Pathogenomics' provides the reader with a global view of key aspects and future trends in bacterial pathogenomics and evaluates their impact on the understanding and treatment of infectious diseases. Well illustrated and accessible to both specialists and nonspecialists, it is recommended not only for researchers in microbiology, genomics and biotechnology, but also for lecturers and teachers.

Pathogenomics


Pathogenomics

Author: Jörg Hacker

language: en

Publisher: John Wiley & Sons

Release Date: 2006-12-13


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The first book on this young, highly dynamic, and expanding field. This comprehensive, interdisciplinary text focuses on those pathogenic bacteria that are of high scientific and public health interest, yet which also display great potential for the development of new diagnostic, prophylactic and therapeutic procedures. The authors cover all aspects of pathogenomics, including methods, genomics and applications. In addition, the ongoing development of genome, transcriptome, proteome and bioinformatic analyses of pathogenic microorganisms and their host interactions makes for a comprehensive introduction to the field of modern genomic analysis. This result is invaluable to researchers and students wishing to gain a general overview of microbial functional genome analysis and pathogenesis, while also representing a good starting point for those new to the area.

Omics, Microbial Modeling and Technologies for Foodborne Pathogens


Omics, Microbial Modeling and Technologies for Foodborne Pathogens

Author: Xianghe Yan

language: en

Publisher: DEStech Publications, Inc

Release Date: 2012


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Provides comprehensive information on genetic analysis and multiple omics methods, microbial modeling, and other technologies used for the analysis of foodborne pathogens. This title details the use of genomics and other omics technologies to study and classify foodborne bacteria, viruses, fungi and protozoa.