Methods In Ipsc Technology

Methods in iPSC Technology

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Methods in iPSC Technology, Volume 9 addresses the different methods used for induced pluripotent stem cell (iPSC) formation, maintenance, expansion, and differentiation. The ability to reprogram different cell types to iPSCs offers an opportunity to generate pluripotent patient-specific cell lines that can help in the understanding of multiple human disorders. This volume addresses a variety of current methods used in the generation and manipulation of iPSCs, such as magnetic nanoparticles, piggyBac vectors, lentiviral vectors, bioscaffolds, somatic cell nuclear transfer, CRISPR/Cas9, bacteria, and much more. This volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and organ transplantation and is contributed by world-renowned authors in the field. - Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine, and therapeutics - Covers the different methods used for iPSC formation, maintenance, expansion, and differentiation - Is contributed by world-renowned experts in the field

Methods and applications in aging neuroscience

Methods in Neurodegenerative Disease Drug Discovery

This book explores the latest developments in the identification of biomarkers for early diagnosis of neurodegenerative diseases and methodologies for the biophysical; in vitro; cell-based; and in vivo profiling, during the early phases of drug discovery, new hits, leads, and drug candidates directed to a variety of biological targets with key pathogenic roles in neurodegenerative diseases. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Comprehensive and thorough, Methods in Neurodegenerative Disease Drug Discovery offers practical guidance to researchers in the medicinal chemistry community. The methods described in this book can be readily implemented in many laboratories and will aid new and experienced researchers with creating future treatments for these devastating diseases.