Metabolomics Perspectives From Theory To Practical Application
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Metabolomics Perspectives
Metabolomics Perspectives: From Theory to Practical Application is an expertly written volume, which provides a thorough description of the current state-of-the-art in the metabolomics field. The philosophy behind the book is to guide the reader in a step-by-step exploration of metabolomics experiments, ranging from sample preparation to data extraction, analysis and interpretation, and to discuss the main current applications and future perspectives of this emerging science. Armed with critical insights, coupled with a clear writing, the book consists of three main sections. The first one introduces the pivotal theoretical fundamentals and provides a comprehensive overview of the "wet" laboratory workflow, including protocol instructions and a detailed description of experimental methods and analytical techniques. The second section covers a wide range of topics in the context of data analysis, including guidance in exploratory analysis, supervised and unsupervised machine learning approaches and validation and optimization methods. In addition to the several examples reported in the text, the book features an R package, specifically designed to perform all the described algorithms, which is hosted on a companion website (www.metabolomicsperspectives.com) together with several sets of available metabolomic data. Finally, an extensive dissertation describes the latest advances and the major fields of interest for metabolomics applications, highlighting their crucial potentials for future biomedical research. Thus, this book represents a must-read for both experienced researchers, interested in metabolomics, and newcomers to the field. - Provides an in-depth description of the metabolomics experimental workflow and its applications in life science and biomedical research - Features chapter contributions from the greatest international experts in the field - Includes an R package and several sets of metabolomics data, hosted on a companion website
Metabolic Dynamics in Host-Microbe Interaction
Author: Sameh S. M. Soliman
language: en
Publisher: Springer Nature
Release Date: 2025-02-05
This book is a ground-breaking that delves into the fascinating world of metabolism and its pivotal role in the survival, attack, and defense strategies in human-microbe interaction. This book explores the intricate biochemical processes that enable organisms to thrive, adapt, and protect themselves against various challenges they encounter in their environments. The book will describe the importance of metabolism in defense and attack by bacteria and fungi in the human microenvironment and the reverse immuno-metabolic responses by the human. Different metabolites from different organisms will be described, in addition to their changes due to interaction with other organisms during infection or defense. The book also will describe the methods of detection and identification of metabolites including metabolomics. The use of artificial intelligence in prediction of metabolic patterns following interaction between different organisms will be included as well. The metabolism in microbiome will be described in relation to infection, and other metabolic diseases, in addition to their effects on therapeutic drugs. The book combines the latest scientific research with accessible explanations, providing readers with a deep understanding of how metabolism empowers organisms to thrive and protect themselves in diverse environments. It will be an invaluable resource for researchers, students, physicians, and anyone fascinated by the wonders of biology and the intricate workings of life.
Analytical Techniques and Methods for Biomass
This book deals with the application of techniques and methods of chemical analysis for the study of biomass and its conversion processes. It aims to fill the existing gap in the literature on this subject. The application of various techniques and analytical methods is presented straightforwardly, enabling readers to choose the most appropriate methodologies for analyzing the major classes of plant biomass and their products. Modern chemistry plays a crucial economic role in industrial activities based on biomass. There is an increasing emphasis on its application, specifically in the development of biorefineries, and the principles of green chemistry allow effective use of biomass while significantly reducing environmental impact. In this context, analytical chemistry can contribute significantly to the supply chains of biomass, be it plant or animal origin. However, biomass from plant sources presents both the greatest challenges and the highest opportunity for technical, scientific, and economic progress due to its diverse chemical constitution. Chemical analysis can be used to examine the composition of biomass, characterize its physicochemical properties, and monitor their conversion processes. This approach can enhance the quality of products derived from biomass and expand their potential applications. The quality of the biomass used determines the product quality. Therefore, reliable information about the chemical composition of the biomass to establish the best use which will influence harvest and preparation steps is essential. Accordingly, this book includes contributions from select international experts who discuss key aspects of biomass structure, their physical and chemical properties, the parameters of conversion processes, the products and by-products formation and quantification, and quality parameters.