Membrane Shape And Biological Function
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Membrane Shape and Biological Function
"For a long time, the main function ascribed to biological membranes was that of being a semi-permeable barrier defining and determining the boundaries between cells and organelles. However, this view has changed. The number of reported essential functions in cell biology ascribed to biological membranes has increased markedly. Indeed, a variety of biological processes rely on the fine-tuned interaction between the membrane and its microenvironment. The functioning of biological membranes is a consequence of the chemical structure and physical properties of the component molecules and their mixtures. One physical property of membranes is their shape. The concept of shape is intimately associated with properties of curvature, but curvature and shape are not necessarily identical. While the role of membrane shape in biological processes was believed to be a passive one, new findings have challenged this view. Membrane shape and shape changes are active ways for the membrane to trigger biological responses. Hence, the coupling between membrane shape and biological function represents a modern aspect of the function of biological membranes. This multidisciplinary book presents state-of-the-art discussions on membrane shape and its relation to biological processes at the intersection of medicine, physics, chemistry, and biology. The book includes fundamentals of membrane shape generation and recognition. In addition, there are chapters that emphasize methods to measure aspects of membrane shape as well as giving specific examples of biological phenomenon that depend on membrane shape with a discussion of the mechanism by which shape determines biological function. The book encompasses theoretical and experimental aspects with examples using model systems and cellular ones. The importance of membrane shape in determining biological function is a relatively new concept that has been rapidly developing in the past several years highlighting the timely importance of this book"--
Membrane Shape and Biological Function
Membrane Shape and Biological Function is an important guide for anyone interested in the dynamic world of biological membranes. The book explores how membrane shape influences crucial biological processes and highlights its practical applications. It delves into the mechanics of lipid bilayers, their role in cellular processes, and computational methods for understanding membrane remodeling, including real-world applications such as the Golgi apparatus' structure and function, the role of inositol phospholipids in cellular organization, membrane fusion in cell biology, and the potential of lipid bilayers in neuromorphic computing. This comprehensive resource is valuable for students, researchers, and anyone curious about membrane biology.
An Introduction to Biological Membranes
Introduction to Biological Membranes: Composition, Structure and Function, Second Edition is a greatly expanded revision of the first edition that integrates many aspects of complex biological membrane functions with their composition and structure. A single membrane is composed of hundreds of proteins and thousands of lipids, all in constant flux. Every aspect of membrane structural studies involves parameters that are very small and fast. Both size and time ranges are so vast that multiple instrumentations must be employed, often simultaneously. As a result, a variety of highly specialized and esoteric biochemical and biophysical methodologies are often utilized. This book addresses the salient features of membranes at the molecular level, offering cohesive, foundational information for advanced undergraduate students, graduate students, biochemists, and membranologists who seek a broad overview of membrane science. - Significantly expanded coverage on function, composition, and structure - Brings together complex aspects of membrane research in a universally understandable manner - Features profiles of membrane pioneers detailing how contemporary studies originated - Includes a timeline of important discoveries related to membrane science