Lectures In Supercomputational Neuroscience
Download Lectures In Supercomputational Neuroscience PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Lectures In Supercomputational Neuroscience book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages.
Lectures in Supercomputational Neuroscience
Computational Neurosciences is a burgeoning field of research where only the combined effort of neuroscientists, biologists, psychologists, physicists, mathematicians, computer scientists, engineers and other specialists, e.g. from linguistics and medicine, seem to be able to expand the limits of our knowledge. The present volume is an introduction, largely from the physicists' perspective, to the subject matter with in-depth contributions by system neuroscientists. A conceptual model for complex networks of neurons is introduced that incorporates many important features of the real brain, such as various types of neurons, various brain areas, inhibitory and excitatory coupling and the plasticity of the network. The computational implementation on supercomputers, which is introduced and discussed in detail in this book, will enable the readers to modify and adapt the algortihm for their own research. Worked-out examples of applications are presented for networks of Morris-Lecar neurons to model the cortical connections of a cat's brain, supported with data from experimental studies. This book is particularly suited for graduate students and nonspecialists from related fields with a general science background, looking for a substantial but “hands-on” introduction to the subject matter.
Neural Fields
Neural field theory has a long-standing tradition in the mathematical and computational neurosciences. Beginning almost 50 years ago with seminal work by Griffiths and culminating in the 1970ties with the models of Wilson and Cowan, Nunez and Amari, this important research area experienced a renaissance during the 1990ties by the groups of Ermentrout, Robinson, Bressloff, Wright and Haken. Since then, much progress has been made in both, the development of mathematical and numerical techniques and in physiological refinement und understanding. In contrast to large-scale neural network models described by huge connectivity matrices that are computationally expensive in numerical simulations, neural field models described by connectivity kernels allow for analytical treatment by means of methods from functional analysis. Thus, a number of rigorous results on the existence of bump and wave solutions or on inverse kernel construction problems are nowadays available. Moreover, neural fields provide an important interface for the coupling of neural activity to experimentally observable data, such as the electroencephalogram (EEG) or functional magnetic resonance imaging (fMRI). And finally, neural fields over rather abstract feature spaces, also called dynamic fields, found successful applications in the cognitive sciences and in robotics. Up to now, research results in neural field theory have been disseminated across a number of distinct journals from mathematics, computational neuroscience, biophysics, cognitive science and others. There is no comprehensive collection of results or reviews available yet. With our proposed book Neural Field Theory, we aim at filling this gap in the market. We received consent from some of the leading scientists in the field, who are willing to write contributions for the book, among them are two of the founding-fathers of neural field theory: Shun-ichi Amari and Jack Cowan.
Computational Systems Neurobiology
Author: N. Le Novère
language: en
Publisher: Springer Science & Business Media
Release Date: 2012-07-20
Computational neurosciences and systems biology are among the main domains of life science research where mathematical modeling made a difference. This book introduces the many different types of computational studies one can develop to study neuronal systems. It is aimed at undergraduate students starting their research in computational neurobiology or more senior researchers who would like, or need, to move towards computational approaches. Based on their specific project, the readers would then move to one of the more specialized excellent textbooks available in the field. The first part of the book deals with molecular systems biology. Functional genomics is introduced through examples of transcriptomics and proteomics studies of neurobiological interest. Quantitative modelling of biochemical systems is presented in homogeneous compartments and using spatial descriptions. A second part deals with the various approaches to model single neuron physiology, and naturally moves to neuronal networks. A division is focused on the development of neurons and neuronal systems and the book closes on a series of methodological chapters. From the molecules to the organ, thinking at the level of systems is transforming biology and its impact on society. This book will help the reader to hop on the train directly in the tank engine.