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Cancer Biomarkers

Tools, techniques, and progress in cancer biomarkers discovery The completion of a number of gene sequencing projects, recent advances in genomic and proteomic technologies, and the availability of powerful bioinformatics tools have led to promising new avenues and approaches in the search for cancer biomarkers. This book provides a comprehensive overview of current methodologies and technologies. It discusses biomarker discovery as a whole, rather than focusing on one specific marker or cancer. With information on both existing and potential biomarkers, Cancer Biomarkers: Analytical Techniques for Discovery: * Provides insights into the current technological platforms for biomarker discovery, including mass spectrometry combined with multidimensional chromatography, DIGE, and various chip technologies * Includes a detailed discussion of protein networks and protein phosphorylation in cancer * Details the use of imaging mass spectrometry, laser capture microdissection, serial analysis of gene expression, enzyme-linked immunosorbent assays, protein microarrays, antibody-based microarrays, and bioinformatics * Covers the emerging role of surface-enhanced laser desorption ionization (SELDI) and various tagging and labeling strategies * Discusses related regulatory and ethical issues With a wealth of information that can be applied to a broad spectrum of biomarker research projects, this is a core reference for biomarker researchers, scientists working in proteomics and bioinformatics, pharmaceutical scientists, oncologists, biochemists, biologists, and chemists.

Power Electronics

Power Electronics is a large size technology, mainly covering four categories: the AC/DC rectifiers, DC/DC converters, DC/AC inverters, and AC/AC converters. This book offers approximately 100 novel topologies of all four. The applications are used in sustainable energy generation areas, such as distributed generation (DG), micro-grid (MG), smart grid (SG) systems, and electrical vehicles (EV). With case studies from GE, AEG, Simplatroll Ltd, and Chinese Power Manufacturing Co., the reader will be exposed to practical applications in industry and real-world settings. This new edition features an entirely new chapter on best switching angles to obtain lowest THD for multilevel DC/AC inverters. Additionally, all chapters have been updated and include homework problems throughout.

Growth Management Study