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Guidelines for the Treatment of Malaria. Third Edition

Author: World Health Organization
language: en
Publisher: World Health Organization
Release Date: 2015-08-13
Malaria remains an important cause of illness and death in children and adults in countries in which it is endemic. Malaria control requires an integrated approach including prevention (primarily vector control) and prompt treatment with effective antimalarial agents. Malaria case management consisting of prompt diagnosis and effective treatment remains a vital component of malaria control and elimination strategies. Since the publication of the first edition of the Guidelines for the treatment of malaria in 2006 and the second edition in 2010 all countries in which P. falciparum malaria is endemic have progressively updated their treatment policy from use of ineffective monotherapy to the currently recommended artemisinin-based combination therapies (ACT). This has contributed substantially to current reductions in global morbidity and mortality from malaria. Unfortunately resistance to artemisinins has arisen recently in P. falciparum in South-East Asia which threatens these gains. This third edition of the WHO Guidelines for the treatment of malaria contains updated recommendations based on a firmer evidence base for most antimalarial drugs and in addition include recommendation on the use of drugs to prevent malaria in groups at high risk. The Guidelines provide a framework for designing specific detailed national treatment protocols taking into account local patterns of resistance to antimalarial drugs and health service capacity. It provides recommendations on treatment of uncomplicated and severe malaria in all age groups all endemic areas in special populations and several complex situations. In addition on the use of antimalarial drugs as preventive therapy in healthy people living in malaria-endemic areas who are high risk in order to reduce morbidity and mortality from malaria. The Guidelines are designed primarily for policy-makers in ministries of health who formulate country-specific treatment guidelines. Other groups that may find them useful include health professionals and public health and policy specialists that are partners in health or malaria control and the pharmaceutical industry. The treatment recommendations in the main document are brief; for those who wish to study the evidence base in more detail a series of annexes is provided with references to the appropriate sections of the main document.
World Health Statistics 2019

World Health Statistics 2019 summarizes recent trends and levels in life expectancy and causes of death, and reports on the health and health-related Sustainable Development Goals (SDGs) and associated targets. Where possible, the 2019 report disaggregates data by WHO region, World Bank income group, and sex; it also discusses differences in health status and access to preventive and curative services, particularly in relation to differences between men and women.
Guidelines for the Treatment of Malaria

Author: World Health Organization
language: en
Publisher: World Health Organization
Release Date: 2006
Malaria is an important cause of death and illness in children and adults in tropical countries, and the mortality rate (which is currently estimated at over a million people per year) has risen in recent years, probably due to increasing resistance to antimalarial medicines. Malaria control requires an integrated approach which covers both prevention (including vector control) and treatment with effective antimalarials. This publication sets out guidelines to help formulate policies and protocols for the treatment of malaria based on sound evidence that can be applied effectively in most settings. Chapters cover: treatment objectives, diagnosis of malaria, resistance to antimalarial medicines, antimalarial treatment policy, treatment of uncomplicated and severe P.falciparum malaria, treatment of P.vivax, P.ovale or P.malariae malaria, mixed malaria infections, complex emergency situations and epidemics.