Introduction To Synthetic Embryology

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Introduction to Synthetic Embryology

In the current era, in which science and technology are advancing by leaps and bounds, we are witness to discoveries and achievements that challenge us to rethink our understanding of life, health and human potential. Remarkable advances in the area of synthetic embryology and gene therapy have been the protagonists of a scientific revolution that takes us beyond the limits of what we previously imagined to be possible. In this book, we explore a vast territory of knowledge, delving into the fascinating domains of creation and modification of living beings, genetic manipulation and embryonic development. The aim is to offer the reader a panoramic and reflective view of the most recent advances in these areas, while raising crucial questions about ethical limits and the ethical and social challenges that accompany these discoveries. Throughout these pages, we delve into the development of gene therapies aimed at combating immune and muscle disorders, delving into the heart of personalized medicine and pointing to a future in which we can correct genetic defects even before birth. We also explore the frontiers between natural embryology and synthetic embryology, confronting traditional conceptions about the beginning of life and the revolutionary possibilities that arise from the manipulation of the fundamental mechanisms of embryonic development. With equal enthusiasm, we examine the applications of synthetic embryology in fields as diverse as creating transgenic foods, adapting organisms to hostile environments, understanding extraterrestrial life, and even colonizing other planets. In doing so, we are confronted with ethical and social dilemmas, the answers to which have the potential to shape not only science, but humanity itself. In each chapter, we seek to present a comprehensive and up-to-date view of scientific and technological advances, always accompanied by a critical and reflective analysis of the ethical implications and challenges we face. Our aim is to provide readers with a starting point for understanding these findings and for informed and constructive debate about the future of synthetic embryology and its implications for society. Therefore, I invite you, dear reader, to embark on this journey of discovery and reflection. As we enter this exciting, uncharted territory of synthetic embryology, we are confronted with profound and provocative questions about the nature of life, our own limits, and the responsibility we carry as custodians of science and innovation. This book is an invitation to explore the frontiers of science and ethics, to challenge our ingrained perceptions and conceptions and, above all, to ponder the future we wish to build. Embark on this journey with us and discover the intriguing and disturbing possibilities that synthetic embryology holds for us.
Examining the State of the Science of Mammalian Embryo Model Systems

Author: National Academies of Sciences, Engineering, and Medicine
language: en
Publisher: National Academies Press
Release Date: 2020-08-31
Because of the recent advances in embryo modeling techniques, and at the request of the Office of Science Policy in the Office of the Director at the National Institutes of Health, the National Academies of Sciences, Engineering, hosted a 1-day public workshop that would explore the state of the science of mammalian embryo model systems. The workshop, which took place on January 17, 2020, featured a combination of presentations, panels, and general discussions, during which panelists and participants offered a broad range of perspectives. Participants considered whether embryo model systems - especially those that use nonhuman primate cells - can be used to predict the function of systems made with human cells. Presentations provided an overview of the current state of the science of in vitro development of human trophoblast. This publication summarizes the presentation and discussion of the workshop.
Stem Cells and the Future of Regenerative Medicine

Author: Institute of Medicine
language: en
Publisher: National Academies Press
Release Date: 2002-01-25
Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.