Introduction To Nanotheranostics
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External Field and Radiation Stimulated Breast Cancer Nanotheranostics
Nano drug-delivery systems responding to cellular local stimuli, such as pH, temperature, reductive agent's activation, i.e. enzymes, could effectively provide passive-mode desirable release but fail in disease treatment following the biological rhythms of brain tumor. Undoubtedly, physical stimulation of functional hybrid nanostructures can release chemotherapeutic cargos more efficiently and could offer an alternative solution as on-demand breast-cancer theranostics. Moreover, remote physical triggering of these nanostructures is more advantageous in terms of improved therapeutics efficiency, spatial and temporal controllability over the chemically stimulated release, the lack of undesirable adverse effects and minimal cargo detachment during the in vivo delivery, etc. This book is a compilation of research development lead by expert researchers and establishes a single reference module. These novel multimodalities can be extremely potent in understanding cancer through real-time observation of drug delivery, release, and activity for non-conventional breast-cancer therapies. In this scenario, the book directly addresses, for the first time, all translational aspects and clinical perspectives of physically stimulated breast-cancer nanotheranostics from a wide-ranging and multidisciplinary perception providing unrivalled and comprehensive knowledge in the field. Part of IPEM-IOP Series in Physics and Engineering in Medicine and Biology.
Nanotheranostics For Personalized Medicine
The application of nanotechnology in the biomedical field, known as nanomedicine, has gained much interest in the recent past as a versatile strategy for selective drug delivery and diagnostic purposes. The nanotheranostic approach, which aims to combine both therapeutic and imaging/diagnostic functionalities, is characterized by a strong pluridisciplinarity where the chemistry of materials, bioconjugate chemistry, pharmaceutical technology, drug delivery, imaging, and pharmacology, work together. Nanotheranostics combine simultaneous non-invasive diagnosis and treatment of diseases with the exciting possibility to monitor drug release and distribution in real time; thus offering the opportunity to optimize treatment outcomes in cancer and other severe diseases. Clinical applications of nanotheranostics would enable earlier detection and treatment of diseases, and earlier assessment of the response, thus allowing to identify patients which would potentially respond to therapy and have higher possibilities of a favorable outcome.Nanotheranostics for Personalized Medicine presents an integrated and transdisciplinary description of nanotheranostics. It provides principles of imaging techniques and concrete examples of advances and challenges in the development of nanotheranostics for personalized medicine.This book is written for students (Bachelors to Doctoral level) as well as experienced researchers, in academia or the industry, interested in this emerging concept in the nanomedicine field.
Introduction to Nanotheranostics
This book offers readers an introduction to the current status of nanoparticles and other nanomaterials that have potential applications in theranostics. Above all, it highlights the diagnostic and therapeutic applications of metallic (e.g. Au, Ag), semiconducting quantum dots (e.g. CdSe, CdTe), magnetic (e.g. Fe3O4, FePt, Co), and multifunctional (combination of two or three) nanoparticles.