Introduction To Membrane Noise
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Introduction to Membrane Noise
Author: Louis J. DeFelice
language: en
Publisher: Springer Science & Business Media
Release Date: 2012-12-06
I started working on membrane noise in 1967 with David Firth in the Department of Physiology at McGill University. I began writing this book in the summer of 1975 at Emory University under a grant from the National Library of Medicine. Part of the writing was also done at the Marine Biological Laboratory Library in Woods Hole and in the Library of the Stazione Zoologica in Naples. I wrote this book because in the intervening years membrane noise became a definable subdivision of membrane biophysics and seemed to deserve a uniform treatment in one volume. Not surprisingly, this turned out to be much more difficult than I had imagined and some areas of the subject that ought to be included have been left out, either for reasons of space or because of my own inability to keep up with all aspects of the field. This book is written for biologists interested in noise and for physicists and electrical engineers interested in biology. The first three chapters attempt to bring both groups to a common point of understanding of electronics and electrophysiology necessary to the study of noise and impedance in membranes. These chapters arose out of a course given over a period of six years to electrical engineers from the Georgia Institute of Technology and biologists from Emory University School of Medicine.
Thermodynamics of Membrane Receptors and Channels
Thermodynamics of Membrane Receptors and Channels synthesizes a wealth of new information regarding the biophysics of membrane proteins. New insights provided by molecular genetics, single channel recording, and high resolution structural techniques are discussed from a conceptual perspective. Basic theoretical topics are introduced, developed, and then extensively illustrated with recent results from the literature or data from the authors' own laboratories. Theoretical and experimental information is incorporated into in-depth discussions of ion permeation mechanisms, ion channel and receptor conformational changes, aggregate activity of complexes of lipids and proteins, and how coupling is achieved between different energy modes in the many transduction systems residing in biomembranes. Thermodynamics of Membrane Receptors and Channels will be valuable both as a learning aid and a reference for biophysicists, neuroscientists, cell biologists, physiologists, and other researchers investigating any aspects of biomembranes.
Squid as Experimental Animals
Author: W.J., Jr. Adelman
language: en
Publisher: Springer Science & Business Media
Release Date: 2013-06-29
The predecessor to this book was A Guide to the Laboratory Use of the Squid Loligo pealei published by the Marine Biological Laboratory, Woods Hole, Massachusetts in 1974. The revision of this long out of date guide, with the approval of the Marine Biological Laboratory, is an attempt to introduce students and researchers to the cephalopods and particularly the squid as an object of biological research. Therefore, we have decided to expand on its original theme, which was to present important practical aspects for using the squid as experimental animals. There are twenty two chapters instead of the original eight. The material in the original eight chapters has been completely revised. Since more than one method can be used for accomplishing a given task, some duplication of methods was considered desirable in the various chapters. Thus, the methodology can be chosen which is best suited for each reader's requirements. Each subject also contains a mini-review which can serve as an introduction to the various topics. Thus, the volume is not just a laboratory manual, but can also be used as an introduction to squid biology. The book is intended for laboratory technicians, advanced undergraduate students, graduate students, researchers, and all others who want to learn the purpose, methods, and techniques of using squid as experimental animals. This is the reason why the name has been changed to its present title. Preceding the chapters is a list of many of the abbreviations, prefixes, and suffixes used in this volume.