Information Theoretic Evaluation For Computational Biomedical Ontologies
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Information-Theoretic Evaluation for Computational Biomedical Ontologies
Author: Wyatt Travis Clark
language: en
Publisher: Springer Science & Business Media
Release Date: 2014-01-09
The development of effective methods for the prediction of ontological annotations is an important goal in computational biology, yet evaluating their performance is difficult due to problems caused by the structure of biomedical ontologies and incomplete annotations of genes. This work proposes an information-theoretic framework to evaluate the performance of computational protein function prediction. A Bayesian network is used, structured according to the underlying ontology, to model the prior probability of a protein's function. The concepts of misinformation and remaining uncertainty are then defined, that can be seen as analogs of precision and recall. Finally, semantic distance is proposed as a single statistic for ranking classification models. The approach is evaluated by analyzing three protein function predictors of gene ontology terms. The work addresses several weaknesses of current metrics, and provides valuable insights into the performance of protein function prediction tools.
Natural Language Processing and Cognitive Science
Author: Bernadette Sharp
language: en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date: 2015-03-10
Peer reviewed articles from the Natural Language Processing and Cognitive Science (NLPCS) 2014 meeting in October 2014 workshop. The meeting fosters interactions among researchers and practitioners in NLP by taking a Cognitive Science perspective. Articles cover topics such as artificial intelligence, computational linguistics, psycholinguistics, cognitive psychology and language learning.
Information Systems Design and Intelligent Applications
The second international conference on INformation Systems Design and Intelligent Applications (INDIA – 2015) held in Kalyani, India during January 8-9, 2015. The book covers all aspects of information system design, computer science and technology, general sciences, and educational research. Upon a double blind review process, a number of high quality papers are selected and collected in the book, which is composed of two different volumes, and covers a variety of topics, including natural language processing, artificial intelligence, security and privacy, communications, wireless and sensor networks, microelectronics, circuit and systems, machine learning, soft computing, mobile computing and applications, cloud computing, software engineering, graphics and image processing, rural engineering, e-commerce, e-governance, business computing, molecular computing, nano-computing, chemical computing, intelligent computing for GIS and remote sensing, bio-informatics and bio-computing. These fields are not only limited to computer researchers but also include mathematics, chemistry, biology, bio-chemistry, engineering, statistics, and all others in which computer techniques may assist.