Implication Of Quorum Sensing System In Biofilm Formation And Virulence
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Implication of Quorum Sensing System in Biofilm Formation and Virulence
Author: Pallaval Veera Bramhachari
language: en
Publisher: Springer
Release Date: 2019-01-28
This book illustrates the importance and significance of Quorum sensing (QS), it’s critical roles in regulating diverse cellular functions in microbes, including bioluminescence, virulence, pathogenesis, gene expression, biofilm formation and antibiotic resistance. Microbes can coordinate population behavior with small molecules called autoinducers (AHL) which serves as a signal of cellular population density, triggering new patterns of gene expression for mounting virulence and pathogenesis. Therefore, these microbes have the competence to coordinate and regulate explicit sets of genes by sensing and communicating amongst themselves utilizing variety of signals. This book descry emphasizes on how bacteria can coordinate an activity and synchronize their response to external signals and regulate gene expression. The chapters of the book provide the recent advancements on various functional aspects of QS systems in different gram positive and gram negative organisms. Finally, the book also elucidates a comprehensive yet a representative description of a large number of challenges associated with quorum sensing signal molecules viz. virulence, pathogenesis, antibiotic synthesis, biosurfactants production, persister cells, cell signaling and biofilms, intra and inter-species communications, host-pathogen interactions, social interactions & swarming migration in biofilms.
Implication of Quorum Sensing and Biofilm Formation in Medicine, Agriculture and Food Industry
Author: Pallaval Veera Bramhachari
language: en
Publisher: Springer Nature
Release Date: 2019-11-26
The book illustrates the role of quorum sensing in the food industry, agriculture, veterinary sciences, and medicine. It highlights the importance of quorum sensing in regulating diverse cellular functions in microbes, including virulence, pathogenesis, controlled-gene expression systems, and antibiotic resistance. This book also describes the role of quorum sensing in survival behavior and antibiotic resistance in bacteria. Further, it reviews the major role played by quorum sensing in food spoilage, biofilm formation, and food-related pathogenesis. It also explores the methods for the detection and quantification of quorum sensing signals. It also presents antimicrobial and anti-quorum sensing activities of medicinal plants. Finally, the book elucidates a comprehensive yet representative description of basic and applied aspects of quorum sensing inhibitors. This book serves an ideal guide for researchers to understand the implications of quorum sensing in the food industry, medicine, and agriculture.
A Complete Guidebook on Biofilm Study
A Complete Guidebook on Biofilm Study has emphasized the biofilm-related issues in the present context related to research and development. For this purpose, experimental design and relevant experimental protocols for the biofilm studies have been highlighted here. In addition to that, inhibitors from natural or synthetic sources against microbial biofilm development have been addressed. This approach has been further substantiated by bioinformatics as well as nanotechnology-based reports. Both, the image processing related to biofilm study and the characters of substratum associated with biofilm development have also been included for a better understanding of the beginners in this field. Further, how biofilm helps and/or hampers in food processing and waste management system, that discussion has been considered in this book. Similarly, human benefits from biofilm and reverse of it have also been included considering host-pathogen interaction, immunity aspects, and others. - Carrying huge resources/information/ideas in a compiled manner for biofilm study/work - Has highlighted how biofilm-related experiment has to be designed based on protocols - This book has focused majorly about biofilm-related gene regulation along with the development of different inhibitors for therapeutic aspects. This paradigm has been further discussed based on the nanotechnology and bioinformatics approach - Biofilm studies related to waste management, food processing, and image processing, which are newly upcoming have been emphasized in this book