Implementation Of High Density Snp Data For Genetic Evaluation And Qtl Discovery In Beef Cattle
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Implementation of High-density SNP Data for Genetic Evaluation and QTL Discovery in Beef Cattle
A genomic relationship matrix was built using 1,707 Angus AI sires with complete pedigree information and 698 Angus steers with only paternity information. The genomic matrix was used to estimate breeding values (EBVs) on both sires and steers and residuals were estimated on the steers. EBV and residuals were combined to produce adjusted phenotypes corrected for fixed effects (year and season of birth within feeding pen) for three feed efficiency related traits (average daily feed intake, AFI; residual feed intake, RFI; and average daily gain, ADG). These dependent variables were used for whole genome association analysis. A genome-wide significance of threshold equivalent to p [lesser than] 0.05 was determined via dependant variable permutation analysis to control experiment wide error rate. Final models for the three traits were assembled using EBVs of steers and explained 54.097%, 62.687% and 54.724% of the genetic variance in AFI, RFI and ADG, respectively. Utility of predicted feed intakes for genetic selection was also tested. Predicted feed intakes (pDMR) were estimated using the Cornell Value Discovery System (CVDS) and were adjusted for fixed effects and EBVs were estimated. Whole genome analysis was performed and concordant SNP associations for ADG, RFI and AFI were identified. Index selection may include pDMR to increase information on feed intake, however correlated responses in ADG are likely if not used within an index.
Molecular and Quantitative Animal Genetics
Animal genetics is a foundational discipline in the fields of animal science, animal breeding, and veterinary sciences. While genetics underpins the healthy development and breeding of all living organisms, this is especially true in domestic animals, specifically with respect to breeding for key traits. Molecular and Quantitative Animal Genetics is a new textbook that takes an innovative approach, looking at both quantitative and molecular breeding approaches. The bookprovides a comprehensive introduction to genetic principles and their applications in animal breeding. This text provides a useful overview for those new to the field of animal genetics and breeding, covering a diverse array of topics ranging from population and quantitative genetics to epigenetics and biotechnology. Molecular and Quantitative Animal Genetics will be an important and invaluable educational resource for undergraduate and graduate students and animal agriculture professionals. Divided into six sections pairing fundamental principles with useful applications, the book's comprehensive coverage will make it an ideal fit for students studying animal breeding and genetics at any level.
Achieving sustainable production of pig meat Volume 2
Author: Emeritus Professor Julian Wiseman
language: en
Publisher: Burleigh Dodds Science Publishing
Release Date: 2017-10-09
Reviews latest research on pig genetics and its implications for improved breeding Detailed review of ways of meeting energy, protein, vitamin and mineral requirements of pigs Assesses the role of exogenous enzymes, growth promotors, prebiotics and probiotics in pig nutrition