Herapeutic Targets


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The DNA Replication Machinery as Therapeutic Targets


The DNA Replication Machinery as Therapeutic Targets

Author: Andrew F. Gardner

language: en

Publisher: Frontiers Media SA

Release Date: 2019-09-19


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In all organisms, the DNA replication machinery is responsible for accurate and efficient duplication of the chromosome. Inhibitors of replication proteins are commonly used in anti-cancer and anti-viral therapies. This eBook on “The DNA Replication Machinery as Therapeutic Targets” examines the normal functions of replication proteins as well as strategies to target each step during the replication process including DNA unwinding, DNA synthesis, and DNA damage bypass and repair. Articles discuss current strategies to develop drugs targeting DNA replication proteins as well as future outlooks and needs.

Identification of Therapeutic Targets and Novel Biomarkers in Prostate Cancer


Identification of Therapeutic Targets and Novel Biomarkers in Prostate Cancer

Author: Shashwat Sharad

language: en

Publisher: Frontiers Media SA

Release Date: 2023-02-08


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Angiogenesis & Therapeutic Targets in Cancer


Angiogenesis & Therapeutic Targets in Cancer

Author: Malay Chatterjee

language: en

Publisher: Bentham Science Publishers

Release Date: 2010


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Angiogenesis plays rate limiting roles in tumor growth and invasion. Angiogenesis inhibition has been proposed as a general strategy to fight against cancers. This book covers different therapeutic targets for angiogenesis interventions with emphasis on c